Drug Abuse and Addiction: Pharmacological Phenomena
Substance Use Disorders Affecting Sleep
Drug Dependence
Stimulants
CNS Depressants: Alcohol and Nicotine
CNS Stimulants: Cocaine, Amphetamines and Cannabinoids
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Updated: May 29, 2026

A Protocol for Measuring Cue Reactivity in a Rat Model of Cocaine Use Disorder
Published on: June 18, 2018
Steve Sussman1, Adam Leventhal, Ricky N Bluthenthal
1Departments of Preventive Medicine and Psychology, University of Southern California, California 90032 CA, USA. ssussma@usc.edu
This study introduces the Pragmatics, Attraction, Communication, and Expectation (PACE) model to explain why individuals develop specific addiction patterns. The PACE model offers a framework for understanding addiction specificity in substance and behavioral addictions.
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