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Updated: May 29, 2026
10:32
Assessing Functional Performance in the Mdx Mouse Model
Published on: March 27, 2014
[Severe muscular dystrophy and pregnancy: interdisciplinary challenge]
F von Breunig1, A E Goetz, K Heckel
1Klinik und Poliklinik für Anästhesiologie, Universitätsklinikum Hamburg-Eppendorf, Martinistr. 52, 20246, Hamburg, Deutschland. fbreunig@uke.de
Der Anaesthesist
|September 13, 2011
Summary
Pregnant women with limb-girdle muscular dystrophy can safely undergo spinal anesthesia for Cesarean delivery. This approach avoids intubation and manages potential respiratory complications effectively.
Area of Science:
- Neurology
- Anesthesiology
- Obstetrics
Background:
- Muscular dystrophies cause progressive muscle weakness, often worsening during pregnancy.
- Pregnant women with muscular dystrophy face increased risks of cardiac and respiratory complications, particularly in later trimesters.
Observation:
- A case report details the successful perioperative management of a pregnant woman with severe limb-girdle muscular dystrophy undergoing Cesarean section.
- The patient was tetraplegic, highlighting the severity of her condition.
Findings:
- Spinal anesthesia with intrathecal hyperbaric bupivacaine was chosen for its controllability.
- Non-invasive positive pressure ventilation was prepared for potential respiratory compromise.
Implications:
- Limb-girdle muscular dystrophy management requires individualized approaches.
- Spinal anesthesia is a viable and safe option for Cesarean delivery in these patients, preventing the need for tracheal intubation.
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