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Updated: May 29, 2026

Full-Field Optical Coherence Microscopy for Histology-Like Analysis of Stromal Features in Corneal Grafts
Published on: October 21, 2022
[Perspectives of deep anterior lamellar keratoplasty]
1Augenklinik des Universitätsklinikums Köln, Universität zu Köln, Joseph-Stelzmann Str. 9, 50924, Köln, Deutschland. claus.cursiefen@uk-koeln.de
Purpose:
The current indications, techniques, results and complications of deep anterior lamellar keratoplasty are described.
Methods:
The study comprised a literature review and own clinical and experimental results.
Results:
The main advantage of DALK in patients with keratoconus and other anterior stromal diseases is the avoidance of endothelial immune reactions and the main drawback is the conversion rate to penetrating keratoplasty of around 15%.
Conclusions:
Using the big bubble approach DALK is a safe and reliable technique for treating keratoconus and anterior stromal dystrophy.
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