Related Experiment Video
Updated: May 29, 2026
09:57
Electromagnetic Source Imaging in Presurgical Evaluation of Children with Drug-Resistant Epilepsy
Published on: September 20, 2024
Seizures in acute childhood stroke
Rani K Singh1, Nassim Zecavati, Jarnail Singh
1Center for Neuroscience, Children's National Medical Center, Washington, DC, USA. ranising@med.umich.edu
The Journal of Pediatrics
|September 14, 2011
Summary
Pediatric stroke patients experiencing seizures within 24 hours face a high risk of developing epilepsy within six months. Early seizure detection is crucial for predicting long-term outcomes in children with acute stroke.
Area of Science:
- Pediatric Neurology
- Neuroscience
- Stroke Research
Background:
- Acute stroke in children is a significant neurological event.
- Seizures are a common complication following pediatric stroke.
- Understanding epilepsy risk is vital for long-term management.
Purpose of the Study:
- To determine the incidence of seizures in pediatric acute stroke.
- To identify predictors for the subsequent development of epilepsy.
- To analyze the timing and characteristics of seizures post-stroke.
Main Methods:
- Retrospective review of pediatric patients (>3.5 years) with acute stroke.
- Data collection on seizure occurrence, type, and timing.
- Analysis of factors associated with epilepsy development at six months.
Main Results:
- 21% of patients presented with clinical seizures; 10% had seizures during hospitalization.
- Status epilepticus was frequent, particularly in infants and those with cortical strokes.
- 24% developed epilepsy within six months, all with initial seizures.
Conclusions:
- Seizures in the first 24 hours of pediatric stroke strongly predict epilepsy development.
- Status epilepticus is common in infants with stroke.
- Prolonged EEG aids in detecting non-convulsive seizures but not epilepsy risk.
Related Concept Videos
01:20Seizures l: Introduction
Understanding seizures and epilepsy relies on key definitions that help in recognizing, classifying, and managing these disorders. These definitions provide a framework for recognizing, classifying, and managing seizure disorders.DefinitionsA seizure is a sudden, abnormal burst of electrical activity in the brain that can cause changes in awareness, movement, sensation, or behavior, depending on the area involved. Epilepsy is a chronic condition characterized by recurrent, unprovoked seizures,...
01:13Seizures: Classification
Epilepsy is primarily characterized by unpredictable seizures, either provoked by an identifiable factor, such as injury or illness, or unprovoked, occurring spontaneously without apparent cause.
Seizures are typically classified into two main categories: focal and generalized seizures.
Focal Seizures
Focal seizures originate from specific regions of the brain. These seizures are further sub-classified into two types:
Seizures are typically classified into two main categories: focal and generalized seizures.
Focal Seizures
Focal seizures originate from specific regions of the brain. These seizures are further sub-classified into two types:
01:19Seizures ll: Types
Seizures are sudden bursts of abnormal electrical discharge in the brain that interfere with normal function. They are commonly divided into three groups: focal seizures, generalized seizures, and other types that do not fit neatly into either category.Focal SeizuresFocal seizures begin in a single brain region. When awareness is preserved, they are called focal aware seizures and may cause sensations such as tingling, unusual smells, or flashing lights. When awareness is impaired, they are...
01:22Epilepsy ll: Types
Recurrent seizures, stemming from abnormal electrical activity in the brain, are the defining characteristic of epilepsy, a chronic neurological condition. Because seizure features vary greatly, epilepsy is classified using two systems: by seizure type and by epilepsy syndromes. These classifications enable clinicians to describe seizure patterns and select suitable treatment strategies.I. Classification by Seizure Type1. Focal EpilepsyFocal epilepsy begins in one hemisphere of the brain.
01:24Epilepsy and Seizures: Overview
Epilepsy is a chronic neurological disease marked by recurrent, unpredictable seizures. These seizures are caused by abnormal electrical discharges in the brain, leading to behavior, sensation, or consciousness alterations. They can also cause transient impairment of awareness, interfering with daily activities.
Various factors can trigger epilepsy, including genetic factors, brain damage, metabolic causes, and unknown etiology. Diagnosis of epilepsy involves electroencephalography (EEG), which...
Various factors can trigger epilepsy, including genetic factors, brain damage, metabolic causes, and unknown etiology. Diagnosis of epilepsy involves electroencephalography (EEG), which...
01:29Stroke: Introduction and Types
A stroke is an acute neurological event caused by the sudden disruption of cerebral blood flow, leading to rapid loss of neuronal function. Neurons depend on continuous oxygen and glucose supply, so even brief interruptions can cause irreversible injury within minutes. Strokes are classified into ischemic and hemorrhagic types.Ischemic StrokeIschemic strokes are most common and occur due to arterial occlusion, depriving brain tissue of oxygen and nutrients. This leads to energy failure, ionic...