Sonographic accuracy in the diagnosis of ovarian masses

Prediction of the tissue diagnosis of ovarian masses has remained a challenge for the sonographer since many adnexal masses have nonspecific sonographic appearances. We evaluated the accuracy of the sonographic diagnosis of adnexal masses in 100 women undergoing laparotomy for ovarian masses within eight weeks of an ultrasound study. Comparison of the preoperative sonographic and final pathologic diagnoses revealed a correct sonographic diagnosis in 68% of the cases. In addition, sonography correctly identified a benign condition in 17% of the cases, though without arriving at the exact tissue diagnosis. Sonography was frankly misleading in 15% of the cases, misreading whether the lesions were benign or malignant. The identification of ovarian malignancy was correct in 24/30 patients (sensitivity, 80%), and the specificity for correctly diagnosing a benign condition was 87%. The positive predictive value of a sonographic diagnosis of an adnexal malignancy was 73%. The negative predictive value of sonography for excluding a malignancy was 91%.