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Diarrhea-related hemolytic uremic syndrome: unmasking antifactor H antibodies

Ankur Gupta1, Ambar Khaira, Om P Rathi

  • 1Department of Nephrology, All India Institute of Medical Sciences, New Delhi, India. parthankur@yahoo.com

Saudi Journal of Kidney Diseases and Transplantation : an Official Publication of the Saudi Center for Organ Transplantation, Saudi Arabia
|September 14, 2011
PubMed

The cases of hemolytic uremic syndrome (HUS) preceeded by diarrhea are commonly labeled as D+ HUS. However, with severe renal failure or with delayed recovery, such cases should be evaluated for rarer associations like Factor H (FH), I and CD 46 deficiency or mutations. We report such a presentation of a young boy who initially came with diarrhea and had features of HUS with delayed renal recovery. He later turned out to have anti-FH antibody-related HUS.

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