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Updated: May 29, 2026

Competing-Risk Nomogram for Predicting Cancer-Specific Survival in Multiple Primary Colorectal Cancer Patients after Surgery
Published on: September 27, 2024
A study of aspects on gender and prognosis in synchronous colorectal cancer
Kristoffer Derwinger1, Bengt Gustavsson
1Sahlgrenska Academy, Department of Surgery, Sahlgrenska University Hospital, Östra 41685 Gothenburg, Sweden.
Aim:
To assess differences in demography, pathology and prognosis with tumor multiplicity in colorectal cancer.
Method:
A retrospective single centre study of all patients surgically treated for a colorectal cancer during 1999-2008 (n = 2524). Patient characteristics, pathology and follow-up data were retrieved. Survival was assessed by overall and cancer specific survival.
Results:
60 (2.4%) patients had a synchronous cancer (SC), associated with right colon, higher age, more assessed lymph nodes but a lower frequency of stage III/IV disease (42% vs. 52%). There was no overall prognostic difference between single or multiple cancer patients but females with SC had better survival than corresponding males (P < 0.046).
Conclusion:
The incidence of synchronous cancers was 2.4% with the second cancer often located in right colon. The SC patients were older than single tumor patients, had a lower frequency of stage III/IV disease and the females with SC had a better survival prognosis than corresponding males.
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