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Median rhomboid glossitis: a clinical and microbiological study
Mustafa Goregen1, Ozkan Miloglu, Mustafa Cemil Buyukkurt
1Assistant Professor, Department of Oral Diagnosis and Radiology, Faculty of Dentistry, Sifa University, Izmir, Turkey.
European Journal of Dentistry
|September 14, 2011
Summary
Median rhomboid glossitis (MRG) is linked to Candida and diabetes mellitus. Other factors like age, gender, smoking, and denture use were not significantly associated with MRG in this study.
Area of Science:
- Oral pathology
- Microbiology
- Dermatology
Background:
- Median rhomboid glossitis (MRG) is a common benign inflammatory condition of the tongue.
- The etiology of MRG remains unclear, with potential roles for fungal and bacterial infections.
- Understanding risk factors is crucial for prevention and management.
Purpose of the Study:
- To investigate the association between median rhomboid glossitis (MRG) and Candida species.
- To determine the prevalence of MRG and its correlation with age, gender, smoking, denture wearing, and diabetes mellitus.
- To differentiate risk factors for MRG from those of general oral candidiasis.
Main Methods:
- Tongue examinations were conducted on 4244 patients.
- 30 patients with MRG and 30 controls were selected for detailed analysis.
- Mycological and bacterial cultures were performed on tongue samples.
Main Results:
- MRG was detected in 0.7% of patients.
- Candida species were found in 90.0% of MRG patients versus 46.6% in controls (p<0.05).
- Diabetes mellitus and the 20-39 age group were significantly associated with MRG.
Conclusions:
- A significant association exists between MRG, Candida, and diabetes mellitus.
- Factors like gender, smoking, and denture use are not significant risk factors for MRG.
- This study helps clarify the specific etiology of MRG, distinguishing it from general oral candidiasis risk factors.
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