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Related Concept Videos

Asthma III: Clinical Manifestations01:13

Asthma III: Clinical Manifestations

Asthma presents with a characteristic pattern of episodic respiratory symptoms that reflect underlying airway inflammation, bronchoconstriction, and mucus hypersecretion. Although severity varies among individuals, certain clinical manifestations are considered hallmarks of the disorder and often guide diagnosis and assessment.Respiratory SymptomsA persistent cough is one of the most common early features of asthma. It is frequently dry and tends to worsen at night or in the early morning,...
Asthma-IV: Diagnostic and Management01:30

Asthma-IV: Diagnostic and Management

The diagnosis and management of asthma are comprehensive, encompassing clinical assessments, lung function tests, and pharmacological interventions. Here's an overview:
Clinical Assessment for Asthma:
This is the first step in diagnosing and managing asthma. It includes:
Asthma: Pathogenesis and Management01:20

Asthma: Pathogenesis and Management

Asthma is a chronic pulmonary condition involving inflammation of the airways, hyper-reactivity, and reversible obstruction of the airways. This condition can significantly impact a person's quality of life, making breathing difficult and leading to distressing symptoms.
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
Asthma-IV: Nursing Management01:30

Asthma-IV: Nursing Management

The nursing management of asthma is a comprehensive approach that relies heavily on the expertise and dedication of healthcare professionals. It involves thorough assessment, accurate diagnosis, strategic planning, effective implementation, and diligent evaluation. By meticulously following this step-by-step process, healthcare professionals play a crucial role in providing the best possible care and treatment for patients with asthma, enhancing their overall health and well-being.
First, in...
Asthma-I: Introduction01:29

Asthma-I: Introduction

Asthma is a chronic respiratory ailment that requires careful management due to its varying symptoms and influencing factors. It is characterized by airway inflammation, bronchial hyperresponsiveness, and reversible airflow obstruction, leading to symptoms like wheezing, shortness of breath, chest tightness, and coughing. The symptom frequency and intensity may vary considerably over time. It is also linked to immune system responses to allergens and irritants, highlighting the complex...
Asthma-II: Pathophysiology and Classification01:26

Asthma-II: Pathophysiology and Classification

Asthma is a prevalent chronic respiratory condition marked by inflammation and hyperresponsiveness of the airways. Its pathophysiology involves complex interactions among inflammatory pathways, immune responses, and neural mechanisms.
Additionally, environmental and genetic factors play crucial roles in determining an individual's susceptibility to asthma and the severity of their condition.
Critical processes in asthma pathophysiology include:

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Updated: May 29, 2026

Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma
14:39

Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma

Published on: November 4, 2010

Asthma Clinical Research Network: lessons learned.

Timothy Craig1, Laura Quinn

  • 1Penn State University, Hershey, PA, USA. tcraig@psu.edu

The Mount Sinai Journal of Medicine, New York
|September 14, 2011
PubMed
Summary
This summary is machine-generated.

The Asthma Clinical Research Network advanced asthma treatment through independent trials. Its findings offer significant insights for current clinical practice.

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Symptom Assessment of Patients with Allergic Rhinitis Using an Allergen Exposure Chamber
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Symptom Assessment of Patients with Allergic Rhinitis Using an Allergen Exposure Chamber

Published on: March 3, 2023

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Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma
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Published on: November 4, 2010

Symptom Assessment of Patients with Allergic Rhinitis Using an Allergen Exposure Chamber
08:47

Symptom Assessment of Patients with Allergic Rhinitis Using an Allergen Exposure Chamber

Published on: March 3, 2023

Area of Science:

  • Pulmonology
  • Clinical Research
  • Public Health

Background:

  • Asthma affects millions globally, necessitating effective treatment strategies.
  • The National Heart, Lung, and Blood Institute established the Asthma Clinical Research Network to address this need.
  • Independent clinical trials are crucial for unbiased evaluation of therapeutic approaches.

Purpose of the Study:

  • To review the experimental design and major findings of key studies from the Asthma Clinical Research Network.
  • To highlight the network's contributions to understanding and treating asthma.
  • To inform current asthma management practices based on robust research.

Main Methods:

  • Systematic review of all publications from the Asthma Clinical Research Network.
  • Selection and summarization of 19 noteworthy studies.
  • Analysis of experimental designs and reported outcomes.

Main Results:

  • The network conducted multicenter clinical trials independently of the pharmaceutical industry.
  • Significant data with important implications for asthma treatment were generated.
  • The research has demonstrably advanced the healthcare community's understanding of asthma.

Conclusions:

  • The Asthma Clinical Research Network has made substantial contributions to asthma research.
  • Findings from the network should impact current asthma treatment protocols.
  • Continued independent research is vital for improving public health outcomes in asthma management.