Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Angle Closure Glaucoma: Treatment

Angle Closure Glaucoma: Treatment

Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...

Photoreceptors and Visual Pathways

Photoreceptors and Visual Pathways

At the molecular level, visual signals trigger transformations in photopigment molecules, resulting in changes in the photoreceptor cell's membrane potential. The photon's energy level is denoted by its wavelength, with each specific wavelength of visible light associated with a distinct color. The spectral range of visible light, classified as electromagnetic radiation, spans from 380 to 720 nm. Electromagnetic radiation wavelengths exceeding 720 nm fall under the infrared category, whereas...

Glaucoma: Overview

Glaucoma: Overview

Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...

Open Angle Glaucoma: Treatment

Open Angle Glaucoma: Treatment

In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...

Allergic Reactions

Allergic Reactions

Allergic Drug Reactions

Allergic Drug Reactions

Allergic reactions related to drugs are hypersensitivity responses driven by the immune system and bear no connection to the drug's therapeutic action. While drugs in isolation do not trigger an immune response, they can interact with endogenous proteins to form antigens. These antigens stimulate lymphocytes to produce antibodies. IgE-type antibodies attach themselves to mast cells. Upon subsequent exposure to the same stimulus, the antigen-antibody interaction is initiated, unleashing numerous...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Unraveling the immune-microbial axis in chronic ocular surface disease.

Current opinion in allergy and clinical immunology·2025

Same author

Bridging diagnostic gaps in anterior ocular inflammatory surface diseases.

Current opinion in allergy and clinical immunology·2025

Same author

From innovation to implementation: strengthening anterior ocular inflammatory surface diseases diagnostics through global health policy.

Current opinion in allergy and clinical immunology·2025

Same author

The Link Between Allergic Rhinitis and Keratoconus: A Call for Greater Awareness, Early Intervention, and Future Ocular Surface Diagnostic Tools.

The journal of allergy and clinical immunology. In practice·2024

Same author

The collaborative medical practice of the ocular surface: a major role of the allergist/immunologist.

Current opinion in allergy and clinical immunology·2024

Same author

Ocular surface disorders: office procedures for the allergist/clinical immunologist.

Current opinion in allergy and clinical immunology·2024

Same journal

Farewell message from Penny A. Asbell, MD, FACS, MBA, Editor-in-Chief of the Mount Sinai Journal of Medicine.

The Mount Sinai journal of medicine, New York·2012

Same journal

Minority undergraduate programs intended to increase participation in biomedical careers.

The Mount Sinai journal of medicine, New York·2012

Same journal

Future of electronic health records: implications for decision support.

The Mount Sinai journal of medicine, New York·2012

Same journal

AA amyloidosis: Mount Sinai experience, 1997-2012.

The Mount Sinai journal of medicine, New York·2012

Same journal

Amyloid neuropathies.

The Mount Sinai journal of medicine, New York·2012

Same journal

Should your family history of coronary heart disease scare you?

The Mount Sinai journal of medicine, New York·2012

See all related articles

Search research articles

Related Experiment Video

Updated: May 29, 2026

Induction of Ocular Surface Inflammation and Collection of Involved Tissues

Induction of Ocular Surface Inflammation and Collection of Involved Tissues

Published on: August 4, 2022

Ocular allergy.

Leonard Bielory¹

¹Center for Environmental Prediction, Rutgers University, Springfield, NJ, USA. bielory@envsci.rutgers.edu

The Mount Sinai Journal of Medicine, New York

|September 14, 2011

Summary

This summary is machine-generated.

Ocular allergic inflammation is common due to the eye's lack of barriers. Advancements in treatments and a collaborative "immuno-ophthalmology" approach are improving patient outcomes for red eye and related allergic conditions.

More Related Videos

Iris Fixation via External Pentagram Suturing

Iris Fixation via External Pentagram Suturing

Published on: May 5, 2022

A Non-invasive Way to Isolate and Phenotype Cells from the Conjunctiva

A Non-invasive Way to Isolate and Phenotype Cells from the Conjunctiva

Published on: July 5, 2017

Related Experiment Videos

Last Updated: May 29, 2026

Induction of Ocular Surface Inflammation and Collection of Involved Tissues

Induction of Ocular Surface Inflammation and Collection of Involved Tissues

Published on: August 4, 2022

Iris Fixation via External Pentagram Suturing

Iris Fixation via External Pentagram Suturing

Published on: May 5, 2022

A Non-invasive Way to Isolate and Phenotype Cells from the Conjunctiva

A Non-invasive Way to Isolate and Phenotype Cells from the Conjunctiva

Published on: July 5, 2017

Area of Science:

Ophthalmology
Allergy and Immunology

Background:

The eye is a frequent site for allergic inflammatory disorders, often presenting as
red eye,
due to direct allergen exposure.
Ocular allergies frequently coexist with other allergic conditions like asthma and eczema.
Ocular symptoms can be the most significant manifestation of a patient's overall allergic response.

Purpose of the Study:

To highlight the prevalence and significance of ocular allergic inflammation.
To discuss the evolution of diagnostic and therapeutic strategies.
To emphasize the benefits of a multidisciplinary approach in managing allergic eye disease.

Main Methods:

Review of recent therapeutic advances in managing ocular allergic inflammation.
Discussion of diagnostic challenges and improved differential diagnoses.
Emphasis on the collaborative
immuno-ophthalmology
model.

Main Results:

Significant therapeutic progress has been made over the past two decades.
Newer treatments include biologic immunomodulatory agents and advanced drug-delivery devices.
Surgical techniques are improving for sight-threatening complications.

Conclusions:

Ocular inflammation is becoming more manageable with current knowledge and treatments.
A team approach involving primary care physicians, ophthalmologists, and allergists/immunologists enhances patient outcomes.
The field of
immuno-ophthalmology
represents a significant advancement in patient care.