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Updated: Aug 18, 2026

A Strategy to Identify de Novo Mutations in Common Disorders such as Autism and Schizophrenia
Published on: June 15, 2011
Models of disease and the diagnosis of schizophrenia
1Hillside Hospital, Long Island Jewish Medical Center, Glen Oaks, NY 11004.
Abstract:
DSM-III criteria for schizophrenia represent a significant advance in diagnostic reliability and relevance to course and treatment outcome. However, the underlying, predominantly biomedical model, if exclusively applied, encourages the making of more malignant diagnoses and in particular the over-diagnosing of schizophrenia. This occurs by virtue of an associated declining interest in the content and context of symptoms, a disavowal of "psychology" and a failure of empathy. A psychodynamic viewpoint can help to redress the diagnostic imbalance that the use of the biomedical model can engender.
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