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Chronic periodontitis with multiple risk factor syndrome: a case report.
Masayuki Shimoe1, Tadashi Yamamoto, Yoshihiro Iwamoto
1Department of Pathophysiology - Periodontal Science, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan.
Journal of the International Academy of Periodontology
|September 15, 2011
Summary
Severe periodontitis, linked to diabetes and hypertension, can worsen cardiovascular health. Comprehensive treatment of both systemic conditions and periodontal disease is crucial for managing patients with multiple risk factor syndrome.
Area of Science:
- Periodontology
- Cardiology
- Endocrinology
Background:
- Multiple risk factor syndrome involves a cluster of cardiovascular risks like diabetes, dyslipidemia, and hypertension, often linked to insulin resistance.
- Severe periodontitis can be a manifestation of underlying systemic health issues.
Observation:
- A patient with a 10-year history of type 2 diabetes, dyslipidemia, and hypertension presented with severe periodontitis and elevated antibodies to Porphyromonas gingivalis.
- Intensive periodontal treatment was initiated, with longitudinal monitoring of systemic and periodontal health over 10 years.
Findings:
- Periodontal treatment led to significant improvements in Porphyromonas gingivalis antibody titers and hemoglobin A1c levels.
- Despite initial improvements, the patient later developed myocardial infarction, with a concurrent decline in hemoglobin A1c and worsening periodontitis.
Implications:
- Long-term clustering of risk factors, including periodontitis, is associated with myocardial infarction development.
- Integrated management of systemic conditions and comprehensive periodontal treatment is vital for patients with multiple risk factor syndrome.
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