Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Color Doppler signals from breast tumors. Work in progress.

D O Cosgrove1, J C Bamber, J B Davey

  • 1Royal Marsden Hospital, London, England.

Radiology
|July 1, 1990
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

High frequency ultrasound vibrational shear wave elastography for preclinical research.

Physics in medicine and biology·2022
Same author

Microflow imaging: New Doppler technology to detect low-grade inflammation in patients with arthritis.

European radiology·2017
Same author

Investigation of In Vivo skin stiffness anisotropy in breast cancer related lymphoedema.

Journal of biomechanics·2015
Same author

Tumour biomechanical response to the vascular disrupting agent ZD6126 in vivo assessed by magnetic resonance elastography.

British journal of cancer·2014
Same author

Can contrast-enhanced ultrasonography characterize focal liver lesions and differentiate between benign and malignant, thus providing a one-stop imaging service for patients?().

Journal of ultrasound·2013
Same author

Guidelines and good clinical practice recommendations for contrast enhanced ultrasound (CEUS) in the liver--update 2012: a WFUMB-EFSUMB initiative in cooperation with representatives of AFSUMB, AIUM, ASUM, FLAUS and ICUS.

Ultraschall in der Medizin (Stuttgart, Germany : 1980)·2012

Color Doppler ultrasound effectively differentiates breast cancer from benign conditions by detecting increased blood flow. This imaging technique shows promise for diagnosing breast lesions, even small cancers.

Area of Science:

  • Medical Imaging
  • Oncology
  • Radiology

Background:

  • Distinguishing malignant from benign breast masses is crucial for timely treatment.
  • Ultrasound is a primary imaging modality for breast lesion assessment.
  • Assessing vascularity may improve diagnostic accuracy.

Purpose of the Study:

  • To evaluate the utility of color Doppler ultrasound in differentiating breast carcinoma from benign breast disorders.
  • To develop and apply a quantitative grading method for assessing blood vessel density in breast masses.

Main Methods:

  • Sixty patients with breast masses underwent subjective assessment and quantitative analysis of color Doppler signals.
  • A regional grading method was used to quantify blood vessel density.
  • Blood flow parameters (vessels/cm², % color pixels) were compared between malignant and benign groups.

Related Experiment Videos

Main Results:

  • Breast carcinoma consistently showed moderate to high blood flow (0.5 vessels/cm², 12.2% color pixels).
  • Benign disorders typically exhibited no or minimal flow (0.01 vessels/cm², 0.8% color pixels).
  • Color Doppler detected flow in cancers as small as 10 mm; high-velocity flow was specific to malignancies.

Conclusions:

  • Color Doppler ultrasound is a valuable tool for the differential diagnosis of breast lesions.
  • Quantitative assessment of blood flow can significantly aid in identifying breast cancer.
  • This technique shows promise as an adjunct to conventional ultrasound imaging.