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Poststeroid panniculitis in an adult
Ana de-Andrés-del-Rosario1, María Magdalena Verea-Hernando, María Teresa Yebra-Pimentel
1Department of Dermatology, Universitary Hospitalary Complex Coruña, A Coruña, Spain. ana.de.andres.del.rosario@sergas.es
The American Journal of Dermatopathology
|September 15, 2011
Summary
Poststeroid panniculitis, a rare condition typically seen in children, can also occur in adults. This case highlights an adult experiencing this inflammatory skin disorder after corticosteroid withdrawal.
Area of Science:
- Dermatology
- Pathology
Background:
- Poststeroid panniculitis is a rare inflammatory condition.
- It is typically observed in pediatric patients following abrupt cessation of corticosteroid therapy.
- Occurrence in adults is exceptionally uncommon.
Observation:
- This report details an unusual case of poststeroid panniculitis in a 34-year-old adult male.
- The patient developed tender subcutaneous nodules on his thighs and legs after discontinuing long-term dexamethasone treatment for a brain tumor.
Findings:
- Histopathology confirmed panniculitis with fat necrosis and characteristic needle-shaped clefts.
- The lesions exhibited both lobular and septal panniculitis with multinucleated giant cells.
Implications:
- This case expands the known demographic of poststeroid panniculitis to include adults.
- It underscores the importance of considering corticosteroid withdrawal as a potential cause of panniculitis in adult patients.
- The findings suggest that weight loss and topical corticosteroids may aid in lesion resolution.
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