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Cerebral venous and sinus thrombosis associated with subcutaneous immunoglobulin injection and oral contraceptive use

Jiangyong Min1, Archit Bhatt, Rany Aburashed

  • 1Division of Cerebral Vascular Diseases, Sparrow Health System, Department of Neurology and Ophthalmology, Michigan State University, A-217 Clinical Center, 138 Service Road, East Lansing, MI 48824, USA. minjy@msu.edu

Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology
|September 15, 2011
PubMed

Although patients of cerebral sinus thrombosis after intravenous immunoglobulin (IVIG) has been previously reported; reports of cerebral venous thrombosis secondary to subcutaneous injection of immunoglobulin (SIG) in conjunction with oral contraceptives are nonexistent in the current literature. We describe here a patient of cerebral venous and sinus thrombosis occurring after the combination of SIG and oral contraceptive use. Furthermore, we shall explore proper clinical precautions for someone who receives IG therapy, especially in conjunction with the use of oral contraceptives.

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