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Semi-Minimal Invasive Method to Induce Myocardial Infarction in Rats and the Assessment of Cardiac Function by an Isolated Working Heart System
Published on: June 11, 2020
[Current strategy of surgical treatment for ischemic heart disease]
Masaru Nishimi1, Tadashi Tashiro
1Department of Cardiovascular Surgery, Fukuoka University, Fukuoka, Japan.
Insights
Off-pump coronary artery bypass grafting (CABG) is prevalent in Japan, with evolving treatments like percutaneous coronary intervention (PCI) and drug-eluting stents (DES) changing surgical strategies for multivessel coronary artery disease.
Area of Science:
- Cardiovascular Surgery
- Interventional Cardiology
Context:
- Coronary artery bypass grafting (CABG) is the standard for multivessel coronary artery disease.
- Off-pump CABG (OPCAB) is increasingly common in Japan (66%), differing from Western practices.
- Percutaneous coronary intervention (PCI) with drug-eluting stents (DES) is rising for complex lesions.
Purpose:
- To address the evolving landscape of ischemic heart disease treatment.
- To outline strategies for maintaining high-quality surgical care amidst changing treatment paradigms.
Summary:
- Focus on arterial grafts for improved graft patency.
- Achieve high rates of complete revascularization through successful multivessel bypass.
- Emphasize meticulous postoperative management to minimize complications.
Impact:
- Shift towards less invasive surgical approaches with maximal therapeutic effects.
- Maintaining surgical quality while adapting to new interventional techniques.
- Improving long-term outcomes for patients with coronary artery disease.
Abstract:
Coronary artery bypass grafting (CABG) surgery is the gold standard therapy for the complete revascularization of patients with multivessel coronary artery disease. Since off-pump CABG (OPCAB) began to be performed, to avoid any side effects from cardiopulmonary bypass, OPCAB is now performed in 66% of all isolated CABG in Japan, and this situation is markedly different from the procedures performed in North America and Europe. Furthermore, percutaneous coronary intervention (PCI) using drug eluting stents (DES) is now being increasingly performed for the treatment of patients with either left main trunk, diffuse or multivessel lesions. Under these circumstances, both the surgical treatment and indications for ischemic heart disease has also changed, and therefore what is asked of surgeons is how they can provide high quality treatment that maintains surgical quality. The strategy to be pursued by surgeons in the future is to perform treatment that is less invasive and provides maximum effects and it is believed that the following issues will become more important. (1) Using arterial grafts for various purposes to maintain high rates graft patency. (2) Successfully performing multivessel bypass procedures and achieving good complete revascularization rates. (3) Careful postoperative management and its complications.
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