Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Endocarditis I: Introduction01:25

Endocarditis I: Introduction

Introduction:Endocarditis is the infection of the endocardium, the inner lining of the heart and its valves. When the heart muscle is involved, the condition is termed myocarditis, while an infection of the outer lining is called pericarditis. Infective endocarditis (IE) primarily affects the endocardium, where pathogens adhere to the valves or lining, forming vegetation that can lead to severe complications. Infective endocarditis occurs when microorganisms, usually bacteria from other body...
Endocarditis II: Clinical Features of Infective Endocarditis01:25

Endocarditis II: Clinical Features of Infective Endocarditis

Endocarditis can present various clinical features depending on the causative organism and the patient's underlying health conditions. Initially, the clinical features of infective endocarditis develop gradually, presenting with nonspecific symptoms that can be easily mistaken for other illnesses.General SymptomsEarly symptoms of infective endocarditis are fever, chills, weakness, malaise, fatigue, and weight loss. These symptoms reflect the systemic nature of the infection and the body's...
Endocarditis IV: Nursing Management01:29

Endocarditis IV: Nursing Management

Infective endocarditis (IE) is a chronic infection of the heart's endocardium, primarily affecting the heart valves. A detailed nursing assessment for a patient with IE involves collecting subjective and objective data to ensure an accurate diagnosis and timely intervention.Subjective DataThe nurse gathers information about the patient's symptoms and complaints during the subjective assessment. Patients with infective endocarditis often report non-specific symptoms that can mimic other...
Endocarditis III: Medical Management01:18

Endocarditis III: Medical Management

Infective endocarditis management involves a multifaceted approach encompassing infection prevention, lifestyle modifications, pharmacological therapy, and surgical management.Infection Prevention:Hand Hygiene: Thorough handwashing is crucial to prevent the spread of infection. Hand hygiene should be performed regularly, especially before and after using the restroom.Oral Hygiene: Good oral hygiene is essential. It includes brushing teeth immediately after waking up and before bed, flossing...
Myocarditis I: Introduction01:21

Myocarditis I: Introduction

Myocarditis is inflammation of the myocardium, which is the muscular layer of the heart.EtiologyMyocarditis has a diverse etiology, including a wide range of infectious and non-infectious causes:Infectious CausesViral: Common viruses include Coxsackie A and B, adenovirus, parvovirus B19, enteroviruses, and influenza A.Bacterial: Examples include infections caused by Streptococcus, Staphylococcus, and Mycoplasma species.Rickettsial: Infections like Rocky Mountain spotted fever can result in...
Rheumatic Heart Disease I: Introduction01:23

Rheumatic Heart Disease I: Introduction

Rheumatic heart disease or RHD is a chronic condition that results from rheumatic fever, causing permanent damage to the heart valves.Etiology and Risk FactorsIt primarily arises from rheumatic fever, an inflammatory disease that can develop after untreated or inadequately treated group A streptococcal (GAS) pharyngitis. Streptococcus spreads through direct contact with oral or respiratory secretions. While the bacteria are the causative agents, factors like malnutrition, overcrowding, poor...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Comparison of the fungal flora in bedding and floor dust.

Journal of microorganism control·2026
Same author

Diffuse large B-cell lymphoma complicated by cytokine release syndrome and immune effector cell-associated neurotoxicity on day 355 of epcoritamab therapy: a case report.

Journal of clinical and experimental hematopathology : JCEH·2026
Same author

A Case of Diffuse Large B-Cell Lymphoma(DLBCL)Who Died of Acute Exacerbation of Interstitial Pneumonia after Treatment with R-mini-CHP in Combination with Polatuzumab Vedotin (Pola-R-mini-CHP).

Gan to kagaku ryoho. Cancer & chemotherapy·2026
Same author

Efficacy and safety of Pola-R-mini-CHP therapy in patients aged ≥80 years with CD5-positive diffuse large B-Cell lymphoma.

Journal of clinical and experimental hematopathology : JCEH·2025
Same author

A Retrospective Study of the Efficacy and Safety of Epcoritamab in Real-world Clinical Practice: An Analysis of 19 Cases from a Single Institution.

Internal medicine (Tokyo, Japan)·2025
Same author

[Efficacy and Safety of R‒mini‒CHP Combined with Polatuzumab‒Vedotin Used for Previously Untreated Diffuse Large B‒Cell Lymphoma in Very Elderly Patients Aged ≥80 Years-A Single‒Center Retrospective Analysis].

Gan to kagaku ryoho. Cancer & chemotherapy·2025

Related Experiment Video

Updated: May 29, 2026

An In Vitro Model of a Parallel-Plate Perfusion System to Study Bacterial Adherence to Graft Tissues
07:50

An In Vitro Model of a Parallel-Plate Perfusion System to Study Bacterial Adherence to Graft Tissues

Published on: January 7, 2019

[Infective endocarditis].

Makoto Hanai1, Kazuhiro Hashimoto

  • 1Department of Cardiac Surgery, Jikei University, Tokyo, Japan.

Kyobu Geka. the Japanese Journal of Thoracic Surgery
|September 16, 2011
PubMed
Summary

Infective endocarditis is increasingly caused by Staphylococcus, including resistant strains. Early surgery is recommended for severe cases, especially with prosthetic valves, to improve outcomes.

Area of Science:

  • Cardiology
  • Infectious Diseases
  • Cardiac Surgery

Context:

  • Infective endocarditis (IE) traditionally linked to Streptococcus species.
  • Recent trends show an increasing prevalence of Staphylococcus species as causative agents.
  • A notable rise in methicillin-resistant Staphylococcus aureus (MRSA) in IE cases presents a significant challenge.

Purpose:

  • To highlight the changing microbial landscape in infective endocarditis.
  • To emphasize the critical role of early surgical intervention in specific IE scenarios.
  • To discuss outcomes and challenges associated with prosthetic valve endocarditis.

Summary:

  • While Streptococcus species remain common, Staphylococcus species, particularly methicillin-resistant strains, are increasingly implicated in infective endocarditis.

More Related Videos

Experimental Endocarditis Model of Methicillin Resistant Staphylococcus aureus (MRSA) in Rat
07:46

Experimental Endocarditis Model of Methicillin Resistant Staphylococcus aureus (MRSA) in Rat

Published on: June 4, 2012

Related Experiment Videos

Last Updated: May 29, 2026

An In Vitro Model of a Parallel-Plate Perfusion System to Study Bacterial Adherence to Graft Tissues
07:50

An In Vitro Model of a Parallel-Plate Perfusion System to Study Bacterial Adherence to Graft Tissues

Published on: January 7, 2019

Experimental Endocarditis Model of Methicillin Resistant Staphylococcus aureus (MRSA) in Rat
07:46

Experimental Endocarditis Model of Methicillin Resistant Staphylococcus aureus (MRSA) in Rat

Published on: June 4, 2012

  • Early surgical intervention is advocated for IE patients with congestive heart failure, antibiotic resistance, or embolism.
  • Mitral valve endocarditis has seen improved results with valve plasty; however, prosthetic valve endocarditis, especially with annular abscess, presents poor outcomes due to complex surgery and recurrence.

    • Impact:

    • Recommends early surgical intervention as a key strategy for improving patient outcomes in complicated infective endocarditis.
    • Highlights the need for improved access to homografts for prosthetic valve endocarditis management.
    • Suggests a shift in treatment paradigms for infective endocarditis due to evolving causative organisms.