[Protein that binds fatty acids (I-FABP)--a new perspective evidence for injury of the small intestine]

Related Experiment Video

Updated: May 29, 2026

Saturated Fatty Acids Induce Ceramide-associated Macrophage Cell Death
08:26

Saturated Fatty Acids Induce Ceramide-associated Macrophage Cell Death

Published on: October 31, 2017

V N Drozdov, I A Li, G G Varvanina

    Eksperimental'Naia I Klinicheskaia Gastroenterologiia = Experimental & Clinical Gastroenterology
    |September 16, 2011
    PubMed

    More Related Videos

    Ileectomy-induced Bile Overaccumulation in Mouse Intestine06:55

    Ileectomy-induced Bile Overaccumulation in Mouse Intestine

    Published on: August 21, 2017

    A Guide to Examining Intramuscular Fat Formation and its Cellular Origin in Skeletal Muscle09:19

    A Guide to Examining Intramuscular Fat Formation and its Cellular Origin in Skeletal Muscle

    Published on: May 26, 2022

    Related Concept Videos

    Lipids as Anchors01:32

    Lipids as Anchors

    In the plasma membrane, the lipids forming the bilayer can also act as an anchor to tether proteins to the membrane. The three main types of lipid anchors found in eukaryotes are – prenyl groups, fatty acyl groups, and glycosylphosphatidylinositol or GPI groups. Prenyl and fatty acyl groups act as anchors on the cytosolic surface of the membrane, whereas GPI anchors proteins on the extracellular side.
    The carboxy-terminal of most of the prenylated proteins, such as Ras proteins, contains the...
    Protein Absorption01:12

    Protein Absorption

    Proteins in the gastrointestinal tract typically come from food, but they can also originate from disintegrated cells or secreted enzymes. In the stomach, the enzyme pepsin breaks down these proteins into polypeptides. The fragments then move into the duodenum as a semi-fluid mass called chyme. Pancreatic proteases, such as trypsin and chymotrypsin, and intestinal brush border enzymes like carboxypeptidases further dismantle the polypeptides into tripeptides, dipeptides, and free amino acids.
    Factors Affecting Protein-Drug Binding: Protein-Related Factors01:20

    Factors Affecting Protein-Drug Binding: Protein-Related Factors

    Drug binding to proteins is a key aspect of pharmacokinetics and can influence a drug's distribution, absorption, and elimination in the body. Several factors, including the drug's physiochemical properties, protein concentration, disease states, and the number of binding sites on the protein, influence this process.
    The physicochemical properties of a drug play a significant role in its ability to bind to proteins. Lipophilic drugs, which dissolve in fats, oils, and lipids, can be bound by...
    Lipid Absorption01:24

    Lipid Absorption

    Dietary triglycerides from chyme in the duodenum are mixed with bile salts produced by the liver to emulsify fats. As a result, large droplets are broken down into smaller ones, increasing the surface area for enzymatic action. Once emulsified, pancreatic lipases hydrolyze the triglycerides into free fatty acids and monoglycerides.
    These breakdown products bind with bile salts and lecithin to form micelles, which quickly pass between microvilli to come in close contact with the apical...
    Acute Pancreatitis II: Pathophysiology01:21

    Acute Pancreatitis II: Pathophysiology

    The pathophysiology of acute pancreatitis centers on injury to pancreatic acinar cells, which initiates a cascade of harmful intracellular events.This injury leads to premature activation of trypsinogen to trypsin in the pancreas. Trypsin then activates other digestive enzymes, such as chymotrypsin, elastase, and phospholipase A2, which begin breaking down pancreatic tissue. The resulting autodigestion causes local inflammation, tissue swelling, hemorrhage, and fat necrosis.Injured acinar cells...
    Chronic Pancreatitis I: Introduction01:24

    Chronic Pancreatitis I: Introduction

    The pancreas, an elongated and flat gland situated behind the stomach, serves a vital function in digesting food and managing blood sugar levels.
    Pancreatitis is the inflammation of the pancreas, which occurs when the immune system becomes active and causes swelling, pain, and disruptions in organ function. Pancreatitis can manifest as either an acute or chronic condition.
    Acute pancreatitis arises suddenly and lasts for a brief duration, while chronic pancreatitis is a long-term affliction...