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Online-calibration for reliable and robust lab-on-a-chip surface enhanced Raman spectroscopy measurement in a

Anne März1, Thomas Bocklitz, Jürgen Popp

  • 1Institute of Physical Chemistry and Abbe Center of Photonics, Friedrich-Schiller University Jena, Jena, Germany.

Analytical Chemistry
|September 16, 2011
PubMed

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A conventional Raman spectrophotometer includes a laser source, a sample holding system, a wavelength selector, and a detector.
The monochromatic laser source, typically using visible or near-infrared radiation, generates a highly focused beam of light. This light interacts with the molecules of the sample, scattering some of the light. Liquid and gaseous samples are usually tested in ordinary glass capillaries, while solids can be analyzed as powders packed in capillaries or as potassium...