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Related Concept Videos

Varicose Veins II: Diagnostic Studies and Interprofessional Care01:26

Varicose Veins II: Diagnostic Studies and Interprofessional Care

Varicose veins, or varicosities, develop when the valves in the veins, which control blood flow, weaken or damage. It causes blood to pool and the veins to enlarge. Understanding the clinical manifestations, diagnostic approaches, and management options for varicose veins is crucial for effective treatment and relief.Clinical manifestationsClinical manifestations of varicose veins include a heavy, achy feeling or pain after prolonged standing or sitting. This discomfort can often be relieved by...
Kidney Transplant II: Surgical Procedure01:26

Kidney Transplant II: Surgical Procedure

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Imaging Studies VII: Vascular Imaging01:19

Imaging Studies VII: Vascular Imaging

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Veins of Head and Neck01:19

Veins of Head and Neck

The blood drainage from the head and neck is primarily managed by three pairs of veins: the external jugular, internal jugular, and vertebral veins. The external jugular veins drain superficial scalp and face structures, passing over the sternocleidomastoid muscles to empty into the subclavian veins.
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Regulation of Angiogenesis and Blood Supply

Rapidly dividing tumors, embryos, and wounded tissues require more oxygen than usual, lowering the oxygen concentration in the blood. At low oxygen or hypoxic conditions, an oxygen-sensitive transcription factor called the hypoxia-inducible factor 1 or HIF1 is activated. HIF1 is a dimeric protein of alpha (ɑ) and beta (β) subunits.  Under optimal oxygen conditions, HIF1β is present in the nucleus while HIF1ɑ remains in the cytosol. HIF1ɑ is hydroxylated by prolyl hydroxylase and factor...
Urinary Tract Calculi VI: Surgical Management01:25

Urinary Tract Calculi VI: Surgical Management

Procedures for Kidney StonesMedical intervention is necessary when kidney stones or renal calculi are too large to pass spontaneously (typically greater than 5 millimeters) when stones are accompanied by symptomatic infection (such as fever or pyelonephritis), when they impair kidney function, or when they cause persistent symptoms like severe pain, nausea, or urinary retention. Additionally, patients with only one kidney or those who cannot be treated with medical management also require...

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Related Experiment Video

Updated: May 29, 2026

Comprehensive Endovascular and Open Surgical Management of Cerebral Arteriovenous Malformations
14:58

Comprehensive Endovascular and Open Surgical Management of Cerebral Arteriovenous Malformations

Published on: October 20, 2017

Oncovascular surgery.

J Ghosh1, A Bhowmick, M Baguneid

  • 1Department of Vascular Surgery, University Hospital of South Manchester, Southmoor Road, Wythenshawe, Greater Manchester, UK. j.ghosh@nhs.net

European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology
|September 16, 2011
PubMed
Summary
This summary is machine-generated.

Major vessel involvement in cancer does not preclude curative surgery. Careful preoperative planning by a multidisciplinary team, including vascular specialists, is essential for successful oncovascular procedures and patient outcomes.

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Pioneering Patient-Specific Approaches for Precision Surgery Using Imaging and Virtual Reality
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Last Updated: May 29, 2026

Comprehensive Endovascular and Open Surgical Management of Cerebral Arteriovenous Malformations
14:58

Comprehensive Endovascular and Open Surgical Management of Cerebral Arteriovenous Malformations

Published on: October 20, 2017

Pioneering Patient-Specific Approaches for Precision Surgery Using Imaging and Virtual Reality
06:18

Pioneering Patient-Specific Approaches for Precision Surgery Using Imaging and Virtual Reality

Published on: April 5, 2024

Area of Science:

  • Oncology
  • Vascular Surgery
  • Surgical Oncology

Background:

  • Surgical resection is the primary curative treatment for cancer.
  • Tumor encasement of major vessels requires specialized planning.
  • Oncovascular surgery addresses cancer resection involving major arterial or venous structures.

Purpose of the Study:

  • To review strategic issues in vascular management for oncovascular surgery.
  • To highlight principles for planning cancer resections involving major blood vessels.

Main Methods:

  • Comprehensive literature search of electronic health databases (Medline, Embase, Scopus).

Main Results:

  • Patient survival depends on complete tumor clearance and tumor biology.
  • Vascular complications do not appear to be the primary determinant of survival.

Conclusions:

  • Major vessel involvement should not prevent en bloc resection for curative intent.
  • Radical surgery offers the best chance for cure or palliation in these complex cases.
  • Multidisciplinary team planning, including vascular specialists, is crucial for optimal patient management.