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Usefulness of adjunctive pulse infusion thrombolysis after failed aspiration for massive intracoronary thrombus

Haruhiko Higashi1, Shinji Inaba, Kazuhisa Nishimura

  • 1Division of Cardiology, Department of Integrated Medicine and Informatics, Ehime University Graduate School of Medicine, and Department of Cardiology, Ehime Prefectural Central Hospital, Ehime, Japan.

The Canadian Journal of Cardiology
|September 16, 2011
PubMed

Insights

Preventing slow/no-reflow in ST-elevation myocardial infarction (STEMI) is crucial. Pulse infusion thrombolysis (PIT) after failed aspiration may effectively manage massive thrombus in STEMI patients.

Area of Science:

  • Cardiology
  • Interventional Cardiology
  • Thrombosis Management

Background:

  • The slow/no-reflow phenomenon complicates emergent percutaneous coronary intervention in ST-elevation myocardial infarction (STEMI).
  • High thrombus burden is a significant predictor of this adverse outcome.
  • Effective management of intracoronary thrombus is critical for improving patient prognosis.

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