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Updated: May 29, 2026

Echocardiographic Evaluation of Atrial Communications before Transcatheter Closure
Published on: February 8, 2022
Transcatheter device closure of a residual postmyocardial infarction ventricular septal defect
Yalım Yalçın1, Cenap Zeybek, Ibrahim Ozgür Onsel
1Department of Pediatric Cardiology, Medicana International Hospital, İstanbul, Turkey.
Insights
This study details a rare case of post-myocardial infarction ventricular septal defect (VSD) successfully treated with a two-stage approach, involving surgical closure and subsequent device closure of a residual shunt.
Area of Science:
- Cardiology
- Cardiovascular Surgery
- Interventional Cardiology
Background:
- Post-myocardial infarction ventricular septal defect (VSD) is a serious complication with high mortality.
- Surgical VSD closure can be challenging, with residual defects being common, necessitating further management.
- This case highlights the management of a complex VSD following acute myocardial infarction.
Observation:
- A 75-year-old female presented with acute anterior myocardial infarction, treated with percutaneous coronary intervention.
- Post-procedure, she developed a hemodynamically significant apical anteroseptal VSD with pulmonary hypertension.
- Initial surgical VSD closure and coronary artery bypass grafting were followed by persistent residual shunt and septicemia.
Findings:
- A residual VSD post-surgical closure required a second intervention.
- A 10-mm Cardio-O-Fix septal occluder was successfully deployed under imaging guidance to close the residual defect.
- The patient stabilized hemodynamically with no significant residual shunt after the device closure.
Implications:
- This case demonstrates the feasibility and success of a hybrid approach for managing residual VSDs after initial surgical repair.
- Percutaneous device closure offers a less invasive option for residual shunts, improving patient outcomes.
- Effective management of post-MI VSD, including residual defects, is crucial for reducing mortality in high-risk cardiac patients.
Abstract:
Postmyocardial infarction ventricular septal defect (VSD) carries a high mortality and, even after successful surgery, residual defect is common. A 75-year-old woman was admitted with the diagnosis of hyperacute anterior myocardial infarction. Primary percutaneous intervention was performed by stenting of a totally obstructed segment in the proximal left anterior descending artery. The patient's condition deteriorated on the second postprocedural day with a 3/6 pansystolic murmur at the mesocardium. Echocardiography revealed an apical anteroseptal VSD and moderate pulmonary hypertension. She underwent surgical VSD closure with a Gore-Tex patch and coronary artery bypass grafting to the left anterior descending and circumflex arteries. The patient's condition continued to be unstable due to septicemia and hemodynamically significant residual VSD. After medical management of septicemia, the residual defect was successfully closed using a 10-mm Cardio-O-Fix septal occluder under fluoroscopic and transesophageal echocardiographic guidance. The clinical condition of the patient was then stabilized and there was no significant residual shunt on echocardiography on the third postprocedural day.
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