Management of HIV and hepatitis C virus infections in resource-limited settings

Ponsiano Ocama1, Emmanuel Seremba

  • 1Department of Medicine, Makerere University College of Health Sciences, Kampala, Uganda. ponsianoocama@yahoo.com

Insights

HIV and hepatitis C virus (HCV) are prevalent in resource-limited settings (RLSs), with regional differences in transmission. Prevention through blood screening and sterile equipment is crucial for curbing spread.

Area of Science:

  • Public Health
  • Infectious Diseases
  • Epidemiology

Background:

  • HIV and Hepatitis C Virus (HCV) pose significant global health challenges.
  • Resource-limited settings (RLSs) bear a disproportionate burden of these infections.

Purpose of the Study:

  • To present an updated review on the epidemiology of HIV and HCV in RLSs.
  • To discuss current management strategies for HIV and HCV in RLSs.

Main Methods:

  • Review of epidemiological data on HIV and HCV prevalence.
  • Analysis of transmission routes in various RLSs.
  • Assessment of management and prevention challenges.

Main Results:

  • Global HIV prevalence is 33.3 million, with 22.5 million in sub-Saharan Africa.
  • Hepatitis C affects 170 million globally, predominantly in RLSs.
  • Transmission modes vary, including injection drug use, medical procedures, and blood transfusions, with rising injection drug use in RLSs.

Conclusions:

  • HIV and HCV are highly prevalent in RLSs, exhibiting regional transmission variations.
  • Effective management is challenged by resource limitations.
  • Prevention strategies, including donor blood screening and sterile instrument use, are vital for controlling transmission.
Abstract

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