Glomerular diseases associated with hematopoietic neoplasms: an expanding spectrum

Once thought to be limited mainly to lesions involving deposition of monoclonal paraproteins, glomerular diseases associated with hematologic neoplasms now include forms in which manifestations are probably mediated through cytokines or chemokines. Said et al. studied one such lesion, myeloproliferative neoplasm-related glomerulopathy, and found it to be a late complication of these neoplasms, with a generally poor renal outcome. Whether earlier recognition of glomerular diseases associated with hematopoietic neoplasms can result in more effective treatment remains an important question.