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Related Concept Videos

Mouse Models of Cancer Study02:43

Mouse Models of Cancer Study

Mice have long served as models for studying human biology and pathology because of their phylogenetic and physiological similarity with humans. They are also easy to maintain and breed in the laboratory, and hence, many inbred strains are now available for research. Studies on mice have contributed immeasurably to our understanding of cancer biology.
The development of transgenic, knockout, and knock-in mice has led to an exponential increase in their use as model organisms in research,...
Mouse Models of Cancer Study02:43

Mouse Models of Cancer Study

Mice have long served as models for studying human biology and pathology because of their phylogenetic and physiological similarity with humans. They are also easy to maintain and breed in the laboratory, and hence, many inbred strains are now available for research. Studies on mice have contributed immeasurably to our understanding of cancer biology.
The development of transgenic, knockout, and knock-in mice has led to an exponential increase in their use as model organisms in research,...
Cancer Survival Analysis01:21

Cancer Survival Analysis

Cancer survival analysis focuses on quantifying and interpreting the time from a key starting point, such as diagnosis or the initiation of treatment, to a specific endpoint, such as remission or death. This analysis provides critical insights into treatment effectiveness and factors that influence patient outcomes, helping to shape clinical decisions and guide prognostic evaluations. A cornerstone of oncology research, survival analysis tackles the challenges of skewed, non-normally...
Treatment Resistent Cancers02:56

Treatment Resistent Cancers

Cancer is the second leading cause of death in the United States. A cancer cell is genetically unstable and hence can mutate faster. They can also modify their microenvironment and escape immune surveillance. The difficulties in treating cancer are further compounded by the emergence of rapid resistance to anticancer drugs. The most common ways to attain resistance in cancer cells include alteration in drug transport and metabolism, modification of drug target, elevated DNA damage response, or...
Treatment Resistant Cancers02:56

Treatment Resistant Cancers

Cancer is the second leading cause of death in the United States. A cancer cell is genetically unstable and hence can mutate faster. They can also modify their microenvironment and escape immune surveillance. The difficulties in treating cancer are further compounded by the emergence of rapid resistance to anticancer drugs. The most common ways to attain resistance in cancer cells include alteration in drug transport and metabolism, modification of drug target, elevated DNA damage response, or...
Clinical Trials01:16

Clinical Trials

Clinical trials are prospective experimental studies conducted on humans to determine the safety and efficacy of treatments, drugs, diet methods, and medical devices. Using statistics in clinical trials enables researchers to derive reasonable and accurate conclusions from the collected data, allowing them to make wise decisions in uncertain situations. In medical research, statistical methods are crucial for preventing errors and bias.
There are four phases in a clinical trial. A phase one...

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Related Experiment Video

Updated: May 29, 2026

Single-Port Robotic-assisted Transaxillary Breast-conserving Surgery: A Prospective, Single-arm, Non-randomized Phase IIa Clinical Trial
03:07

Single-Port Robotic-assisted Transaxillary Breast-conserving Surgery: A Prospective, Single-arm, Non-randomized Phase IIa Clinical Trial

Published on: August 19, 2025

Multicenter breast cancer collaborative registry.

Simon Sherman1, Oleg Shats, Elizabeth Fleissner

  • 1Eppley Institute for Research in Cancer, University of Nebraska Medical Center, Omaha, NE, USA.

Cancer Informatics
|September 16, 2011
PubMed
Summary
This summary is machine-generated.

The Breast Cancer Collaborative Registry (BCCR) streamlines data collection for breast cancer research. This certified system supports developing better diagnostic, prevention, and treatment strategies for breast cancer patients and survivors.

Keywords:
biomedical informaticsbreast cancercaBIG® bronze compatible systemregistry

More Related Videos

Studying Triple Negative Breast Cancer Using Orthotopic Breast Cancer Model
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Studying Triple Negative Breast Cancer Using Orthotopic Breast Cancer Model

Published on: March 20, 2020

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Last Updated: May 29, 2026

Single-Port Robotic-assisted Transaxillary Breast-conserving Surgery: A Prospective, Single-arm, Non-randomized Phase IIa Clinical Trial
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Single-Port Robotic-assisted Transaxillary Breast-conserving Surgery: A Prospective, Single-arm, Non-randomized Phase IIa Clinical Trial

Published on: August 19, 2025

Studying Triple Negative Breast Cancer Using Orthotopic Breast Cancer Model
09:29

Studying Triple Negative Breast Cancer Using Orthotopic Breast Cancer Model

Published on: March 20, 2020

Area of Science:

  • Biomedical Informatics
  • Cancer Research
  • Health Informatics

Background:

  • Breast cancer research requires efficient data management systems.
  • Existing systems may lack standardization for data collection and reporting.
  • Multicenter collaboration is crucial for comprehensive breast cancer studies.

Purpose of the Study:

  • To describe the Breast Cancer Collaborative Registry (BCCR), a multicenter web-based system for breast cancer data.
  • To highlight the BCCR's technical architecture and data standardization approach.
  • To emphasize the registry's role in advancing breast cancer diagnostics, prevention, treatment, and survivorship.

Main Methods:

  • Utilizes a multi-tier web application with Java Servlet/JSP and an Oracle 11g database.
  • Incorporates harmonized controlled vocabulary with NCI Thesaurus (NCIt) and SNOMED-CT.
  • Achieved National Cancer Institute's caBIG Bronze compatibility certification.

Main Results:

  • The BCCR facilitates rapid and uniform collection of critical information and biological samples.
  • Currently involves seven cancer institutions with data on nearly 900 subjects (patients, survivors, high-risk individuals).
  • Provides a standardized approach to data collection and reporting for breast cancer research.

Conclusions:

  • The BCCR is a valuable, certified resource for multicenter breast cancer research.
  • Standardized data collection through BCCR supports the development of improved breast cancer strategies.
  • The registry's infrastructure promotes efficient data sharing and analysis for advancing breast cancer care.