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Updated: May 29, 2026

Topical Airway Anesthesia for Awake-endoscopic Intubation Using the Spray-as-you-go Technique with High Oxygen Flow
Published on: January 13, 2017
[Live-threatening bronchospasm during anesthesia induction : when pure routine becomes a nightmare]
1Klinik für Anästhesiologie mit Schwerpunkt operative Intensivmedizin, Charité-Universitätsmedizin Berlin, Campus Benjamin Franklin, Deutschland. anne.rueggeberg@charite.de
A severe asthma attack caused life-threatening respiratory failure during anesthesia induction in an 18-year-old female. Prompt treatment with multiple medications stabilized her oxygen saturation, leading to a full recovery.
Area of Science:
- Anesthesiology
- Pulmonology
- Emergency Medicine
Background:
- A young female with a history of asthma and milk protein allergy presented for abscess incision.
- A prior event, initially thought to be an asthmatic attack, was retrospectively identified as cardiac arrest requiring mechanical ventilation.
Observation:
- During anesthesia induction, the patient experienced sudden, severe bronchospasms, rendering ventilation impossible.
- Oxygen saturation plummeted to critically low levels (below 80%, nadir 13%) over 12 minutes.
Findings:
- The patient received emergency treatment including epinephrine, corticosteroids, antihistamines, beta-agonists, ketamine, and methylxanthines.
- Oxygen saturation normalized within 15 minutes of treatment initiation.
- Mechanical ventilation was required for a total of 4 days post-event, following 24 hours of therapeutic hypothermia.
Implications:
- The event was ultimately diagnosed as near-fatal asthma, not anaphylactic shock to propofol.
- Patient's underreporting of asthma history, due to a desire for independence, potentially contributed to the severity of the event.
- Highlights the importance of thorough patient history and recognizing severe asthma exacerbations in perioperative settings.
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