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Updated: May 29, 2026

Biochemical Reconstitution of Steroid Receptor•Hsp90 Protein Complexes and Reactivation of Ligand Binding
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BAG-1 diversely affects steroid receptor activity

Regina T Knapp1, Andrea Steiner, Ulrike Schmidt

  • 1Max Planck Institute of Psychiatry, Kraepelinstrasse 10, 80804 Munich, Germany.

The Biochemical Journal
|September 17, 2011
PubMed
Summary

Bcl-2-associated athanogene 1 (BAG-1) isoforms BAG-1L and BAG-1M inhibit progesterone receptor (PR) activity, requiring the heat-shock protein 70-binding domain. BAG-1M also binds and inhibits the mineralocorticoid receptor (MR).

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