Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Negative and Cognitive Symptoms of Schizophrenia01:30

Negative and Cognitive Symptoms of Schizophrenia

Negative symptoms of schizophrenia indicate a reduction or absence of typical behaviors and emotional responses found in healthy individuals, while positive symptoms reflect an excess or distortion of normal functioning.
Negative Symptoms
Negative symptoms of schizophrenia manifest as deficits in normal emotional and behavioral functioning, profoundly impacting daily life. Individuals with schizophrenia often display a flat affect, characterized by a near-total absence of emotional expression,...
Dementia l: Introduction01:22

Dementia l: Introduction

Dementia is an acquired, progressive syndrome characterized by a decline in multiple cognitive domains severe enough to impair daily functioning and reduce independence. Although memory loss is a central feature, the diagnosis requires additional deficits involving language, executive function, visuospatial skills, judgment, calculation, or abstract reasoning. These cognitive impairments reflect underlying neurodegenerative or vascular processes that gradually disrupt neuronal networks...
Dementia01:30

Dementia

Dementia is a collective term for cognitive disorders primarily affecting memory, thinking, and reasoning. It is not a specific disease but a syndrome, with Alzheimer's disease being the most common cause, accounting for approximately 60-80% of cases. Other types include vascular dementia, Lewy body dementia, and frontotemporal dementia. Dementia affects millions worldwide, particularly older adults, though it is not a normal part of aging.
The progression of dementia is generally gradual.
Alzheimer Disease l: Introduction01:29

Alzheimer Disease l: Introduction

Alzheimer disease is a chronic, progressive, and irreversible neurodegenerative disorder and the most common cause of dementia in older adults. It leads to gradual neuronal loss, causing cognitive decline, behavioral changes, and loss of functional independence.Risk Factors and EtiologyThe disease is multifactorial. Age is the strongest risk factor, with prevalence doubling every 5 years after age 65. Genetic factors include mutations in genes such as APP, PSEN1, and PSEN2, which are associated...
Cognitive Development During Adulthood01:30

Cognitive Development During Adulthood

Cognitive development continues throughout adulthood, undergoing significant shifts across early, middle, and late stages. Individual transition occurs from adolescent idealism to pragmatic and adaptable thinking in early adulthood. During this period, individuals learn to integrate personal beliefs with the recognition that other perspectives are equally valid. Exposure to the complexities of modern society, diverse experiences, and higher education contribute to this adaptive thought process,...
Higher Mental Functions of Brain: Learning and Memory01:26

Higher Mental Functions of Brain: Learning and Memory

Memory is one of the most vital higher mental functions of the brain. Memory is closely related to learning because it enables us to retain information and experiences from our past to use them in our present life. It also helps us to remember facts, events, and skills, such as riding a bike or swimming. There are two types of memory — declarative memory, which involves memorizing facts or events, and procedural memory, which enables us to remember how to do something like writing or playing an...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Digital maze test reveals cognitive performance patterns associated with amyloid-β and tau.

Neuropsychology·2026
Same author

Plasma phosphorylated tau 217 and longitudinal trajectories of Aβ, tau, and cognition in cognitively unimpaired older adults.

Nature communications·2026
Same author

Baseline cortical amyloid-β levels are associated with subsequent study-partner-rated apathy in community-dwelling older adults.

Journal of Alzheimer's disease : JAD·2026
Same author

Combining p-tau217 and digital cognitive testing to predict cognitive decline.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2026
Same author

The prognostic value of blood-based p-tau217 levels on progression to clinical impairment.

medRxiv : the preprint server for health sciences·2026
Same author

Whole blood gene expression moderates associations between AD biomarkers and cognitive decline in cognitively unimpaired older adults.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2026

Related Experiment Video

Updated: May 29, 2026

Transcranial Direct Current Stimulation (tDCS) for Memory Enhancement
10:37

Transcranial Direct Current Stimulation (tDCS) for Memory Enhancement

Published on: September 18, 2021

Specific subjective memory complaints in older persons may indicate poor cognitive function.

Rebecca England Amariglio1, Mary K Townsend, Francine Grodstein

  • 1Department of Neurology, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA.

Journal of the American Geriatrics Society
|September 17, 2011
PubMed
Summary
This summary is machine-generated.

Subjective memory complaints (SMCs) correlate with objective cognitive decline. Specific memory issues, not all complaints, predict cognitive impairment, with more complaints indicating worse cognitive function.

More Related Videos

Highlighting and Reducing the Impact of Negative Aging Stereotypes During Older Adults' Cognitive Testing
06:58

Highlighting and Reducing the Impact of Negative Aging Stereotypes During Older Adults' Cognitive Testing

Published on: January 24, 2020

Assessment of Age-related Changes in Cognitive Functions Using EmoCogMeter, a Novel Tablet-computer Based Approach
10:13

Assessment of Age-related Changes in Cognitive Functions Using EmoCogMeter, a Novel Tablet-computer Based Approach

Published on: February 14, 2014

Related Experiment Videos

Last Updated: May 29, 2026

Transcranial Direct Current Stimulation (tDCS) for Memory Enhancement
10:37

Transcranial Direct Current Stimulation (tDCS) for Memory Enhancement

Published on: September 18, 2021

Highlighting and Reducing the Impact of Negative Aging Stereotypes During Older Adults' Cognitive Testing
06:58

Highlighting and Reducing the Impact of Negative Aging Stereotypes During Older Adults' Cognitive Testing

Published on: January 24, 2020

Assessment of Age-related Changes in Cognitive Functions Using EmoCogMeter, a Novel Tablet-computer Based Approach
10:13

Assessment of Age-related Changes in Cognitive Functions Using EmoCogMeter, a Novel Tablet-computer Based Approach

Published on: February 14, 2014

Area of Science:

  • Gerontology
  • Cognitive Neuroscience
  • Epidemiology

Background:

  • Subjective memory complaints (SMCs) are common in older adults.
  • Understanding the link between perceived memory issues and objective cognitive performance is crucial for early detection of cognitive impairment.

Purpose of the Study:

  • To investigate the association between the type and number of subjective memory complaints (SMCs) and objective cognitive test performance.

Main Methods:

  • Cross-sectional study of 16,964 women (mean age 74) from the Nurses' Health Study.
  • Telephone cognitive assessments and SMC questionnaires were administered.
  • Multivariable regression models analyzed cognitive impairment and test scores, adjusting for age and depressive symptoms.

Main Results:

  • Certain SMCs, like difficulty in conversations or navigation, were strongly linked to cognitive impairment.
  • The number of SMCs showed a linear relationship with poorer cognitive test scores.
  • Each additional SMC increased the odds of cognitive impairment by approximately 20%.

Conclusions:

  • Subjective memory complaints are significantly associated with objective cognitive status.
  • SMCs can serve as a valuable indicator for primary care physicians to consider further cognitive evaluation.