Related Experiment Video

Updated: May 29, 2026

Following in Real Time the Impact of Pneumococcal Virulence Factors in an Acute Mouse Pneumonia Model Using Bioluminescent Bacteria
11:32

Following in Real Time the Impact of Pneumococcal Virulence Factors in an Acute Mouse Pneumonia Model Using Bioluminescent Bacteria

Published on: February 23, 2014

Prenatal and postnatal risk factors for infantile pneumonia in a representative birth cohort

C H Chen1, H J Wen, P C Chen

  • 1Department of Environmental and Occupational Medicine, National Taiwan University Hospital, Taipei, Taiwan.

Epidemiology and Infection
|September 17, 2011
PubMed

Insights

Infant pneumonia risk factors like preterm birth, congenital issues, and prenatal smoke exposure were identified in a large survey. Understanding these factors is crucial for reducing infant mortality and morbidity.

Area of Science:

  • Pediatrics
  • Public Health
  • Environmental Health

Background:

  • Pneumonia is a significant cause of infant mortality and morbidity.
  • Limited data exists on risk factors for pneumonia in infants under six months.
  • This study addresses the knowledge gap by investigating risk factors in a large population.

Purpose of the Study:

  • To evaluate risk factors associated with infantile pneumonia.
  • To determine the contribution of identified risk factors.
  • To provide data for preventative strategies against infant pneumonia.

Main Methods:

  • A large population-based survey involving 21,248 main caregivers.
  • Structured questionnaires collected data on family environment, medical history, and hospitalization.
  • Multivariate logistic regression analysis was employed to identify risk factors.

Main Results:

  • Prevalence of pneumonia was 0.62% in the study cohort.
  • Identified risk factors include preterm birth, congenital cardiopulmonary disease, prenatal antibiotic use, maternal overweight, prenatal environmental tobacco smoke exposure, maternal smoking during pregnancy, and home mold.
  • These factors are significantly associated with infantile pneumonia.

Conclusions:

  • Several environmental and medical factors are linked to infantile pneumonia.
  • Preterm birth, congenital conditions, and prenatal exposures are key risk factors.
  • Further research is needed to confirm causality and explore mechanisms of these novel factors.

More Related Videos

A Mouse Model for the Transition of Streptococcus pneumoniae from Colonizer to Pathogen upon Viral Co-Infection Recapitulates Age-Exacerbated Illness12:21

A Mouse Model for the Transition of Streptococcus pneumoniae from Colonizer to Pathogen upon Viral Co-Infection Recapitulates Age-Exacerbated Illness

Published on: September 28, 2022

Related Concept Videos

Pneumonia I: Introduction01:30

Pneumonia I: Introduction

Pneumonia is an acute respiratory infection that targets the lungs, specifically the alveoli. These tiny air sacs, essential for oxygen exchange, become engorged with pus and fluid, severely hindering breathing, decreasing oxygen absorption, and causing significant pain and discomfort during respiration.
Risk Factors
Various factors influence the likelihood of developing pneumonia. Age plays a crucial role, with infants, children under two, and individuals over 65 at increased risk due to their...
Pneumonia I: Introduction01:29

Pneumonia I: Introduction

Pneumonia is an infection of the lower respiratory tract that leads to inflammation of the lung parenchyma, often resulting in the accumulation of inflammatory exudate in the alveoli and airways. Unlike the watery, low-protein fluid exudate in pulmonary edema, the exudate in this case is a thick fluid rich in immune cells, proteins, and debris produced during infection and inflammation.This impairs gas exchange and can lead to consolidation of lung tissue. The infection may be caused by a...
Pneumonia V: Nursing management and Prevention01:30

Pneumonia V: Nursing management and Prevention

Nursing management of pneumonia involves promoting airway patency, facilitating rest and conserving energy, encouraging fluid intake, maintaining nutrition, and educating patients.
The nurse must practice strict medical asepsis and adhere to infection control guidelines to minimize healthcare-associated infections.
Enhance airway patency
Position the patient correctly to facilitate drainage of the affected lung segments. Manual or mechanical percussion and vibration can also be employed.
Pneumonia III: Complications and Assessment01:30

Pneumonia III: Complications and Assessment

Pneumonia poses the potential for numerous complications that warrant consideration. These complications include the following:
Atypical Pneumonia01:14

Atypical Pneumonia

Atypical pneumonia, often caused by Mycoplasma pneumoniae, is a form of pulmonary infection that differs from the classical presentation of bacterial pneumonia in both its cause and clinical symptoms. Mycoplasma pneumoniae is a pleomorphic bacterium notable for its lack of a rigid cell wall. This structural characteristic imparts resistance to beta-lactam antibiotics and significantly influences the bacterium’s behavior within the human host.Other pathogens responsible for the disease include...
Pneumonia II: Pathophysiology01:29

Pneumonia II: Pathophysiology

The pathophysiology of pneumonia involves the following steps: