Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Deep learning-based detection of murine congenital heart defects from µCT scans.

Communications biology·2025
Same author

Author Correction: Inactivation of cytidine triphosphate synthase 1 prevents fatal auto-immunity in mice.

Nature communications·2025
Same author

Criss cross heart: an outflow tract defect?

Orphanet journal of rare diseases·2025
Same author

Plasticity of ventricle position after heart looping in heterotaxy with right isomerism.

Science advances·2025
Same author

Notch3 is an asymmetric gene and a modifier of heart looping defects in Nodal mouse mutants.

PLoS biology·2025
Same author

Pseudodynamic analysis of heart tube formation in the mouse reveals strong regional variability and early left-right asymmetry.

Nature cardiovascular research·2024

Related Experiment Video

Updated: May 29, 2026

A Method for Lineage Tracing of Corneal Cells Using Multi-color Fluorescent Reporter Mice
07:48

A Method for Lineage Tracing of Corneal Cells Using Multi-color Fluorescent Reporter Mice

Published on: December 18, 2015

Tracing cells for tracking cell lineage and clonal behavior.

Margaret E Buckingham1, Sigolène M Meilhac

  • 1Molecular Genetics of Development Unit, CNRS URA 2578, Department of Developmental Biology, Institut Pasteur, Paris, France. margaret.buckingham@pasteur.fr

Developmental Cell
|September 17, 2011
PubMed
Summary
This summary is machine-generated.

Understanding cell lineage is key for development and stem cell research. New genetic engineering and imaging tools enable advanced clonal analysis for tracking cell development.

More Related Videos

Lineage Tracing and Clonal Analysis in Developing Cerebral Cortex Using Mosaic Analysis with Double Markers (MADM)
09:25

Lineage Tracing and Clonal Analysis in Developing Cerebral Cortex Using Mosaic Analysis with Double Markers (MADM)

Published on: May 8, 2020

Live Imaging Followed by Single Cell Tracking to Monitor Cell Biology and the Lineage Progression of Multiple Neural Populations
10:55

Live Imaging Followed by Single Cell Tracking to Monitor Cell Biology and the Lineage Progression of Multiple Neural Populations

Published on: December 16, 2017

Related Experiment Videos

Last Updated: May 29, 2026

A Method for Lineage Tracing of Corneal Cells Using Multi-color Fluorescent Reporter Mice
07:48

A Method for Lineage Tracing of Corneal Cells Using Multi-color Fluorescent Reporter Mice

Published on: December 18, 2015

Lineage Tracing and Clonal Analysis in Developing Cerebral Cortex Using Mosaic Analysis with Double Markers (MADM)
09:25

Lineage Tracing and Clonal Analysis in Developing Cerebral Cortex Using Mosaic Analysis with Double Markers (MADM)

Published on: May 8, 2020

Live Imaging Followed by Single Cell Tracking to Monitor Cell Biology and the Lineage Progression of Multiple Neural Populations
10:55

Live Imaging Followed by Single Cell Tracking to Monitor Cell Biology and the Lineage Progression of Multiple Neural Populations

Published on: December 16, 2017

Area of Science:

  • Cell Biology
  • Developmental Biology
  • Stem Cell Research

Background:

  • Cell lineage reconstruction is fundamental to understanding biological development.
  • It is also a critical area of investigation in modern stem cell research.
  • Tracking cell development and differentiation is essential for regenerative medicine.

Purpose of the Study:

  • To highlight the importance of cell lineage reconstruction in developmental and stem cell biology.
  • To discuss the impact of technological advancements on clonal analysis.
  • To explore new possibilities in prospective and retrospective clonal analysis.

Main Methods:

  • Utilizing genetically engineered permanent cell labeling techniques.
  • Employing a variety of fluorescent markers for cellular tracking.
  • Leveraging sophisticated imaging technologies for detailed observation.

Main Results:

  • Technological advances have significantly improved the capabilities for clonal analysis.
  • New methods allow for both prospective (future-oriented) and retrospective (past-oriented) tracking of cell lineages.
  • Enhanced precision in observing cell behavior and differentiation pathways.

Conclusions:

  • Advanced cell labeling and imaging technologies are revolutionizing cell lineage studies.
  • These tools provide unprecedented opportunities for understanding developmental processes and stem cell behavior.
  • The potential for detailed clonal analysis is crucial for future research in regenerative medicine and developmental biology.