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Published on: November 6, 2019
[Consensus document on the diagnosis and treatment of acute tonsillopharyngitis]
R Piñeiro Pérez1, F Hijano Bandera, F Alvez González
1Sociedad Española de Infectología Pediátrica, España. roipineiro@telefonica.net
Insights
Acute tonsillopharyngitis, a common childhood illness, is often viral. Bacterial infections, primarily Group A Streptococcus, require targeted antibiotic treatment based on clinical scores and testing to prevent overuse.
Area of Science:
- Pediatrics
- Infectious Diseases
- Microbiology
Background:
- Acute tonsillopharyngitis is a frequent childhood illness, predominantly viral.
- Group A Streptococcus (Streptococcus pyogenes) is the primary bacterial pathogen.
- Over-diagnosis and unnecessary antibiotic prescriptions are concerns.
Framework:
- Diagnostic testing (culture or rapid antigen-detection test) should be guided by clinical scores.
- Treatment objectives include symptom reduction, decreased contagion, and prevention of complications.
- Antibiotic therapy should be reserved for confirmed bacterial cases.
Implementation:
- If rapid antigen-detection tests are unavailable or negative, throat cultures are recommended.
- Empirical antibiotic treatment is advised for high clinical suspicion.
- Penicillin is the preferred antibiotic; amoxicillin is an alternative first-line option.
Implications:
- Amoxicillin/clavulanate is not recommended for empirical treatment.
- Macrolides are reserved for penicillin-allergic patients or streptococcal carriers.
- Evidence-based antibiotic prescribing is crucial for managing tonsillopharyngitis.
Abstract:
Acute tonsillopharyngitis is one of the most common childhood diseases. Viruses are the most frequent origin. Group A Streptococcus (Streptococcus pyogenes) is the main bacterial cause. A culture or a rapid antigen-detection test of a throat-swab specimen should only be done on the basis of clinical scores, in order to avoid over-diagnosis of bacterial origin and unnecessary antibiotic prescription. The objectives of treatment are: the reduction of symptoms, reduce the contagious period, and prevent local suppurative and systemic complications. Ideally, only confirmed cases should receive antibiotics. If there is no possibility to perform a rapid antigen-detection test, or in some cases if the result is negative, it is recommended to perform a culture and, if there is high suspicious index, to prescribe antibiotics. Penicillin is the treatment of choice, although amoxicillin is also accepted as the first option. Amoxicillin/clavulanate is not indicated in any case as empirical treatment. Macrolides are not a first choice antibiotic, and should be reserved for those patients with immediate penicillin allergy reaction or for the treatment of streptococcal carriers. It is of primordial importance to adapt the prescribing of antibiotics to the scientific evidence.
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