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Deep brain stimulation for Dejerine-Roussy syndrome: case report
1Department of Neurosurgery, Hospital Beneficência Portuguesa, São Paulo, Brazil. raphaelvalves@yahoo.com.br
Minimally Invasive Neurosurgery : MIN
|September 17, 2011
Summary
Deep brain stimulation offers a potential treatment for central post-stroke pain, a neuropathic condition often refractory to conventional therapies. This minimally invasive procedure may improve quality of life for select patients.
Area of Science:
- Neurosurgery
- Neurology
- Pain Management
Background:
- Central post-stroke pain (CPSP) is neuropathic pain following a cerebrovascular accident.
- Patients experience symptoms like burning, lacerating, and shooting pain.
- Current treatment options for CPSP are limited in efficacy.
Observation:
- A case report details a 47-year-old male patient with treatment-refractory CPSP.
- The patient underwent deep brain stimulation targeting the left centromedian thalamic nuclei using the Leksell frame.
- Qualitative symptomatic improvement was observed post-procedure.
Findings:
- Deep brain stimulation (DBS) can be effective for intractable central post-stroke pain.
- Thalamic DBS targeting the centromedian nuclei shows promise for CPSP management.
- Minimally invasive neurosurgery can provide relief when other treatments fail.
Implications:
- DBS represents a viable therapeutic option for carefully selected patients with severe CPSP.
- This neurosurgical intervention may significantly enhance the quality of life for individuals with refractory neuropathic pain.
- Further research into optimal DBS targets and parameters for CPSP is warranted.

