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Related Concept Videos

Capillary Electrophoresis: Applications01:30

Capillary Electrophoresis: Applications

Capillary electrophoretic separations offer various modes, each with unique applications. These modes include capillary zone electrophoresis, capillary gel electrophoresis, capillary array electrophoresis, capillary isoelectric focusing, capillary isotachophoresis, micellar electrokinetic chromatography, and capillary electrochromatography.
Capillary zone electrophoresis (CZE) separates ionic components based on their electrophoretic mobility. It has been used to separate proteins, amino acids,...
Electrophoresis: Overview01:20

Electrophoresis: Overview

Electrophoresis is a powerful analytical separation technique that relies on the differential migration of charged species when subjected to an electric field. The core strength of electrophoresis lies in its ability to separate high-molecular-weight species in complex mixtures. It has found widespread use in biochemistry, molecular biology, and analytical chemistry, allowing the separation of compounds like amino acids, nucleotides, carbohydrates, and proteins with excellent resolution.
There...
Capillary Electrophoresis: Instrumentation01:20

Capillary Electrophoresis: Instrumentation

Capillary electrophoresis instrumentation typically consists of several key components. A high-voltage power supply generates the electric field necessary for the separation by connecting to an anode (the positively charged electrode) and a cathode (the negatively charged electrode) located in buffer reservoirs at each end of the capillary tube. The system includes a sample vial, a fused silica capillary tube coated with polyimide for mechanical strength through which the sample components...
Two-dimensional Gel Electrophoresis01:22

Two-dimensional Gel Electrophoresis

Two-dimensional gel electrophoresis is a high-resolution protein separation method first introduced by O' Farrell and Klose in 1975. This method involves protein separation by two dimensions, mass and charge, making it more accurate than one-dimensional gel electrophoresis.
The first dimension separation uses the isoelectric focusing or IEF technique performed on immobilized pH gradient (IPG) strips that separate proteins according to their isoelectric points.
Biological samples, such as  cells...

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Related Experiment Video

Updated: May 29, 2026

Separating Beads and Cells in Multi-channel Microfluidic Devices Using Dielectrophoresis and Laminar Flow
09:45

Separating Beads and Cells in Multi-channel Microfluidic Devices Using Dielectrophoresis and Laminar Flow

Published on: February 4, 2011

Dielectrophoresis in microfluidics technology.

Barbaros Cetin1, Dongqing Li

  • 1Mechanical Engineering, Middle East Technical University, Northern Cyprus Campus, Güzelyurt, Turkey. barbaros.cetin@bilkent.edu.tr

Electrophoresis
|September 17, 2011
PubMed
Summary

Dielectrophoresis (DEP) manipulates particles using non-uniform electric fields. This review analyzes DEP modeling and microfluidic applications from 2007-2010.

Area of Science:

  • Physics
  • Electrical Engineering
  • Biotechnology

Background:

  • Dielectrophoresis (DEP) is a phenomenon describing particle movement in non-uniform electric fields.
  • DEP leverages particle dipole interaction with electric field gradients for manipulation.
  • Its effectiveness at the microscale makes it suitable for microfluidic systems.

Purpose of the Study:

  • To provide a detailed analysis of the modeling techniques for DEP-based particle manipulation.
  • To review recent applications of DEP in microfluidic systems, focusing on literature from 2007-2010.

Main Methods:

  • Review of existing scientific literature on dielectrophoresis.
  • Analysis of mathematical models describing DEP forces and particle behavior.
  • Categorization and summary of reported applications in microfluidics.

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Label-free Isolation and Enrichment of Cells Through Contactless Dielectrophoresis
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Label-free Isolation and Enrichment of Cells Through Contactless Dielectrophoresis

Published on: September 3, 2013

Digital Microfluidics for Automated Proteomic Processing
10:55

Digital Microfluidics for Automated Proteomic Processing

Published on: November 6, 2009

Related Experiment Videos

Last Updated: May 29, 2026

Separating Beads and Cells in Multi-channel Microfluidic Devices Using Dielectrophoresis and Laminar Flow
09:45

Separating Beads and Cells in Multi-channel Microfluidic Devices Using Dielectrophoresis and Laminar Flow

Published on: February 4, 2011

Label-free Isolation and Enrichment of Cells Through Contactless Dielectrophoresis
10:38

Label-free Isolation and Enrichment of Cells Through Contactless Dielectrophoresis

Published on: September 3, 2013

Digital Microfluidics for Automated Proteomic Processing
10:55

Digital Microfluidics for Automated Proteomic Processing

Published on: November 6, 2009

Main Results:

  • Comprehensive overview of DEP modeling approaches.
  • Identification of key trends and advancements in microfluidic particle manipulation using DEP between 2007 and 2010.

Conclusions:

  • DEP is a powerful technique for microscale particle and cell manipulation.
  • Understanding DEP modeling is crucial for designing effective microfluidic devices.
  • Recent literature highlights diverse applications of DEP in microfluidics.