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TORCH screening in polyhydramnios: an observational study.

Humera Fayyaz¹, Junaid Rafi

¹Obstetrics & Gynaecology Department, Scarborough General Hospital, Woodlands Drive Scarborough, North Yorkshire, YO12 6QL, United Kingdom.

The Journal of Maternal-Fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians

|September 20, 2011

Summary

The TORCH test is not significantly beneficial for diagnosing infections in women with isolated polyhydramnios, particularly in the third trimester. This study found no positive TORCH infections in women with polyhydramnios.

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Area of Science:

Medical Diagnostics
Infectious Diseases in Pregnancy
Maternal-Fetal Medicine

Background:

Polyhydramnios, an excess of amniotic fluid, can be associated with fetal infections.
The TORCH panel (Toxoplasmosis, Other infections like Syphilis, Rubella, Cytomegalovirus, Herpes Simplex Virus) is used to screen for these infections.

Purpose of the Study:

To evaluate the diagnostic significance of the TORCH test in singleton pregnancies complicated by polyhydramnios.
To determine if TORCH screening is beneficial for pregnant women presenting with polyhydramnios.

Main Methods:

Retrospective analysis of TORCH test indications and results from November 2007 to 2009.
Detailed review of case notes for women with polyhydramnios who underwent TORCH testing.

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Main Results:

Out of 3004 deliveries, 110 (3.6%) had TORCH screening, with polyhydramnios being the primary indication (56.36%).
Only one case of Cytomegalovirus (CMV) infection was detected (in a patient with deranged LFTs, not isolated polyhydramnios).
No TORCH infections were confirmed in women screened for polyhydramnios (p <0.0001), with no associated maternal or perinatal mortality.

Conclusions:

The TORCH test showed no significant benefit for pregnant women with isolated polyhydramnios, especially when diagnosed in the third trimester.
While the study size is small, current statistical evaluation suggests limited utility of the TORCH test in this specific obstetric context.