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Bone morphogenetic protein 7: a broad-spectrum growth factor with multiple target therapeutic potency

Mariëtte R Boon1, Geertje van der Horst, Gabri van der Pluijm

  • 1Department of General Internal Medicine, Endocrinology and Metabolic Diseases, Leiden University Medical Center, Leiden, The Netherlands. m.r.boon@lumc.nl

Cytokine & Growth Factor Reviews
|September 20, 2011
PubMed
Summary

Bone morphogenetic protein 7 (BMP7) is a pleiotropic growth factor vital for bone, kidney, and adipose tissue development. Aberrant BMP7 expression links to diseases like osteoarthritis and renal fibrosis, highlighting its therapeutic potential.

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