Related Experiment Video
Updated: May 29, 2026
05:47
Repetitive Transcranial Magnetic Stimulation to the Unilateral Hemisphere of Rat Brain
Published on: October 22, 2016
Temporal changes in brain MRI findings in Rasmussen syndrome
Etsuko Yamazaki1, Yukitoshi Takahashi, Noriyuki Akasaka
1National Epilepsy Center, Shizuoka Institute of Epilepsy and Neurological Disorders, Shizuoka, Japan. yama@szec.hosp.go.jp
Epileptic Disorders : International Epilepsy Journal with Videotape
|September 20, 2011
Summary
Magnetic Resonance Imaging (MRI) can reveal dynamic lesion changes, aiding Rasmussen syndrome (RS) diagnosis. Evolutionary patterns like lesion regression, fluctuation, and expansion are key MRI characteristics for identifying RS.
Area of Science:
- Neurology
- Radiology
- Medical Imaging
Background:
- Rasmussen syndrome (RS) diagnosis relies heavily on MRI for early detection and surgical planning.
- Understanding MRI characteristics is crucial for accurate RS evaluation.
Purpose of the Study:
- To examine the status and evolutionary changes in MRI lesions in Rasmussen syndrome patients.
- To identify specific MRI characteristics indicative of RS.
Main Methods:
- Analyzed MRI scans of 15 RS patients.
- Assessed frequency and distribution of atrophic lesions (T1-weighted images) and high-intensity lesions (FLAIR/T2-weighted images).
Main Results:
- Atrophic lesions were common, primarily in frontal lobes.
- High-intensity lesions appeared in the cortex, insula, and subcortical white matter, with prevalence varying by onset and seizure type (EPC/non-EPC).
- Serial MRI showed lesion regression, fluctuation, and expansion, often correlating with seizure activity; bilateral lesions were seen in surgically treated cases.
Conclusions:
- Dynamic evolutionary changes in MRI lesions, including regression, fluctuation, and expansion of high-intensity lesions, are potential diagnostic features of Rasmussen syndrome.
- MRI findings provide valuable insights into disease progression and can guide treatment decisions.
