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Related Experiment Videos

Wilms tumor in adolescence.

K Shah, S Wasan, S Lott

    The Journal of Urology
    |March 1, 1979
    PubMed
    Summary
    This summary is machine-generated.

    Wilms tumor is rare in adolescents, often presenting with symptoms mimicking other conditions. This review highlights the importance of considering Wilms tumor in older children and teenagers.

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    Area of Science:

    • Pediatric Oncology
    • Nephrology

    Background:

    • Wilms tumor (nephroblastoma) is a pediatric kidney cancer predominantly diagnosed in children under 5 years old.
    • Adolescent Wilms tumor cases are infrequent, leading to potential diagnostic delays or misdiagnoses.

    Observation:

    • Literature review and case series indicate Wilms tumor rarity in adolescence.
    • Analysis of Ontario Cancer Foundation data (1973-1975) showed 3 of 17 cases were adolescents (16-17 years).
    • Further review of 316 registered cases revealed only 5 patients aged 15-19 years.

    Findings:

    • Adolescent Wilms tumor is often not considered in the differential diagnosis due to its rarity.
    • Symptoms in older patients can mimic other conditions such as neuroblastoma, renal cell carcinoma, or acute abdominal pathologies.

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  • Comparison with pediatric renal cell carcinoma shows a similar, albeit small, incidence in the 15-18 year age group.

    • Implications:

    • Clinicians should maintain a high index of suspicion for Wilms tumor in adolescents presenting with abdominal masses or related symptoms.
    • Early consideration of Wilms tumor in the differential diagnosis for older children can lead to timely diagnosis and treatment.
    • Further research may elucidate specific factors contributing to adolescent Wilms tumor presentation and outcomes.