Related Experiment Video
Updated: Aug 7, 2026
10:26
A Multicenter MRI Protocol for the Evaluation and Quantification of Deep Vein Thrombosis
Published on: June 2, 2015
Ioversol in ascending phlebography--a clinical trial
1Prince Henry Hospital, Sydney.
Australasian Radiology
|February 1, 1990
Summary
Ioversol-240 and ioversol-320 demonstrated comparable diagnostic quality and safety in venography. Both contrast agent strengths showed high patient tolerance with minimal adverse events, making them suitable for diagnostic imaging.
Area of Science:
- Radiology and Medical Imaging
- Contrast Media Research
Background:
- Venography is a crucial diagnostic imaging technique.
- Ioversol is a non-ionic, low-osmolar iodinated contrast agent used in various radiological procedures.
Purpose of the Study:
- To compare the diagnostic quality, safety, and patient tolerance of two ioversol strengths (ioversol-240 and ioversol-320) in venography.
Main Methods:
- A controlled, randomized, double-blind, parallel-group study.
- Involved venography procedures using either ioversol-240 or ioversol-320.
- Assessed diagnostic quality, patient-reported tolerance (heat, pain), vital signs, laboratory parameters, and adverse reactions.
Main Results:
- Diagnostic quality was comparable between the ioversol-240 and ioversol-320 groups.
- High patient tolerance was observed, with only mild heat reported in a small number of patients.
- No clinically significant changes in vital signs or laboratory parameters were noted, and no serious adverse reactions occurred.
Conclusions:
- Both ioversol-240 and ioversol-320 are effective and well-tolerated contrast agents for venography.
- The study supports the use of both ioversol strengths in diagnostic venography with a favorable safety profile.
More Related Videos
08:05Occlusion of the Great and Small Saphenous Vein Using Copolymeric Glue Based on N-Butyl Cyanoacrylate and Methacryloxy Sulfolane
Published on: December 9, 2022
07:53Quantifying Inferior Vena Cava Compliance and Distensibility in an In Vivo Ovine Model Using 3D Angiography
Published on: April 26, 2024
Related Concept Videos
01:16Clinical Trials
Clinical trials are prospective experimental studies conducted on humans to determine the safety and efficacy of treatments, drugs, diet methods, and medical devices. Using statistics in clinical trials enables researchers to derive reasonable and accurate conclusions from the collected data, allowing them to make wise decisions in uncertain situations. In medical research, statistical methods are crucial for preventing errors and bias.
There are four phases in a clinical trial. A phase one...
There are four phases in a clinical trial. A phase one...
01:11Clinical Trials: Overview
Clinical development focuses on how the drug will interact with the human body and encompasses four key phases of clinical trials, each serving a specific purpose in assessing the safety and effectiveness of new drugs. These phases overlap and build upon one another. Phase I involves a small group of healthy volunteers (typically 20-80 individuals) or, in cases where significant toxicity is expected, patients with the targeted disease, such as cancer or AIDS. The volunteers are tested for...
01:28Esophageal Varices-II: Clinical Features and Management
Esophageal varices often manifest as gastrointestinal bleeding episodes, presenting symptoms like hematemesis (vomiting of blood), hematochezia (passing fresh blood via the rectum), and melena (black, tarry stools). Other signs can include weight loss, anorexia, abdominal discomfort, jaundice, pruritus, altered mental status, and muscle cramps.
In the initial assessment, a thorough review of the patient's medical history is vital to identify risk factors such as liver disease, alcohol abuse, or...
In the initial assessment, a thorough review of the patient's medical history is vital to identify risk factors such as liver disease, alcohol abuse, or...
01:26Varicose Veins I: Introduction
Varicose veins, or varicosities, are abnormally dilated and twisted superficial veins caused by venous valve incompetence. This condition commonly affects the lower extremities, especially the saphenous veins, due to the higher pressure from prolonged standing and walking. However, varicosities can also occur in other areas, such as the esophagus, vulva, spermatic cords, and anorectal region.Etiology and typesPrimary varicose veins, often idiopathic, are more common in women due to inherent...
01:26Varicose Veins II: Diagnostic Studies and Interprofessional Care
Varicose veins, or varicosities, develop when the valves in the veins, which control blood flow, weaken or damage. It causes blood to pool and the veins to enlarge. Understanding the clinical manifestations, diagnostic approaches, and management options for varicose veins is crucial for effective treatment and relief.Clinical manifestationsClinical manifestations of varicose veins include a heavy, achy feeling or pain after prolonged standing or sitting. This discomfort can often be relieved by...
01:20Venous Thrombosis II: Clinical Manifestations and Diagnostic Studies
The key difference between Superficial Vein Thrombosis (SVT) and Deep Vein Thrombosis (DVT) lies in their location and severity.Clinical ManifestationsSVT typically presents with localized pain, tenderness, and redness along the course of a superficial vein, often accompanied by a palpable, cord-like structure under the skin. This condition is usually less dangerous than DVT but can be uncomfortable and may lead to complications such as cellulitis or, rarely, a clot extension into the deep...