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A study of depersonalisation neurosis
S Khanna1, R Ramasubbu, S M Channabasavanna
1Junior Resident, Department of Psychiatry, N.I.M.H.A.N.S., Bangalore - 560 029.
Depersonalisation neurosis, a condition affecting young males, often presents insidiously with a deteriorating course. Tricyclic antidepressants showed better efficacy than amphetamines in treating this disorder.
Area of Science:
- Psychiatry
- Neuroscience
Background:
- Depersonalisation neurosis is a complex psychiatric condition.
- Understanding its clinical presentation and treatment is crucial.
Purpose of the Study:
- To investigate the characteristics of depersonalisation neurosis.
- To evaluate treatment responses in affected individuals.
Main Methods:
- Retrospective study of 12 cases diagnosed with depersonalisation neurosis over 6.5 years.
- Analysis of clinical symptoms, disease course, and treatment outcomes.
Main Results:
- The condition predominantly affected young males, often with an insidious onset and deteriorating course.
- Commonly associated symptoms included anxiety, depression, derealisation, deaffectualisation, and sleep/appetite disturbances.
- A classification of depersonalisation into 7 groups was attempted.
- Tricyclic antidepressants demonstrated a better treatment response compared to amphetamines.
Conclusions:
- Depersonalisation neurosis presents with a distinct clinical profile in young males.
- Pharmacological interventions, particularly tricyclic antidepressants, may offer therapeutic benefits.
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