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Updated: May 29, 2026

Antibody Binding Specificity for Kappa (Vκ) Light Chain-containing Human (IgM) Antibodies: Polysialic Acid (PSA) Attached to NCAM as a Case Study
Published on: June 29, 2016
Serum immunoglobulins and schizophrenia
I V Rao1, P S Gopinath, N Jayasimha
1Senior Resident, Department of Psychiatry, National Institute of Mental Health and Neurosciences Bangalore - 560 029.
Abstract:
Fifty four schizophrenic patients, diagnosed as per Research Diagnostic Criteria, were studied for immunoglobulin profiles. The schizophrenics were subdivided into paranoid and non-paranoid groups and their immunoglobulin profiles were compared with those of normals. There was no significant difference between normals and schizophrenic groups. Duration of illness, previous episodes of schizopnrenia, family history of schizophrenia severity of psychosis and duration of hospital stay had no influence on serum IgG, IgA and IgM in schizophrenics. The results are discussed in the light of existing literature on immunoglobulin alterations in schizophrenia.
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