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Related Concept Videos

Obsessive-Compulsive Disorder01:28

Obsessive-Compulsive Disorder

Obsessive-compulsive disorder (OCD) is a mental health condition characterized by recurrent obsessions, compulsions, or both, which consume significant time and interfere with daily functioning. Obsessions involve persistent, intrusive, and unwanted thoughts, images, or urges that evoke anxiety. Common examples include irrational fears of contamination or harm. Compulsions are repetitive behaviors or mental acts performed to reduce the anxiety caused by obsessions. For instance, individuals...
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Hierarchy of Motor Control01:18

Hierarchy of Motor Control

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Anxiety: Overview

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Control System Problem01:21

Control System Problem

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Related Experiment Video

Updated: May 29, 2026

Signal Attenuation as a Rat Model of Obsessive Compulsive Disorder
09:29

Signal Attenuation as a Rat Model of Obsessive Compulsive Disorder

Published on: January 9, 2015

Obsessive compulsive disorder: is it a problem of complex motor programming?

S Khanna1, C R Mukundan, S M Channabasavanna

  • 1Resident, Department of Psychiatry, National Institute of Mental Health and Neurosciences, Bangalore - 560 029.

Indian Journal of Psychiatry
|September 20, 2011
PubMed
Summary
This summary is machine-generated.

Obsessive compulsive disorder (OCD) is linked to altered brain activity. This study found differences in Bereitschaftspotential, suggesting a neurophysiological basis for motor programming dysfunction in OCD patients.

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Exploring the Neural Correlates of Cognitive Reappraisal in Obsessive-Compulsive Disorder Using Task-based Functional Magnetic Resonance Imaging
09:14

Exploring the Neural Correlates of Cognitive Reappraisal in Obsessive-Compulsive Disorder Using Task-based Functional Magnetic Resonance Imaging

Published on: March 14, 2025

Area of Science:

  • Neuroscience
  • Psychiatry
  • Neurophysiology

Background:

  • Obsessive compulsive disorder (OCD) is a mental health condition characterized by intrusive thoughts and repetitive behaviors.
  • Understanding the neurophysiological underpinnings of OCD is crucial for developing targeted treatments.

Purpose of the Study:

  • To investigate neurophysiological differences between individuals with OCD and healthy controls.
  • To examine the Bereitschaftspotential (readiness potential) as a potential biomarker for OCD-related dysfunction.

Main Methods:

  • Compared 44 subjects with OCD and 40 healthy controls using an experimental paradigm.
  • Recorded and analyzed the Bereitschaftspotential (readiness potential) in both groups.

Main Results:

  • Individuals with OCD exhibited a decreased onset latency and increased amplitude of the Bereitschaftspotential compared to controls.
  • These findings suggest alterations in the neurophysiological processes associated with motor programming in OCD.

Conclusions:

  • The study implicates a dysfunction in complex motor programming in OCD.
  • This dysfunction may be localized to the prefrontal area, offering insights into OCD pathophysiology.
  • Findings were discussed in relation to Gilles de la Tourette syndrome and focal neurophysiological dysfunction.