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Related Concept Videos

Electrocardiogram01:29

Electrocardiogram

An electrocardiogram (ECG or EKG) is a critical diagnostic tool that records the electrical signals produced by the heart during each heartbeat. This recording is achieved through electrodes placed strategically on the arms, legs, and chest. The electrocardiograph amplifies these signals and produces 12 distinct tracings, offering a comprehensive understanding of the heart's electrical activity.
Three major waveforms are present in a typical ECG recording: the P wave, the QRS complex, and the T...
ECG Interpretation of Arrhythmias II: Atrial, Junctional and Ventricular Arrhythmias01:25

ECG Interpretation of Arrhythmias II: Atrial, Junctional and Ventricular Arrhythmias

Arrhythmia is a condition characterized by an irregular heart rhythm, with ECG changes that differ based on its origin and nature. The types of arrhythmias discussed below include atrial, junctional, and ventricular arrhythmias.Atrial ArrhythmiasPremature Atrial Complexes (PACs): PACs are early atrial beats caused by stress, caffeine, alcohol, electrolyte imbalances, hypoxia, hyperthyroidism, or certain medications (e.g., bronchodilators and decongestants). The ECG shows early P waves with an...
Disturbances in Heart Rhythm01:29

Disturbances in Heart Rhythm

Arrhythmia or dysrhythmia refers to an abnormal heart rhythm caused by a defect in the heart's conduction system. It can cause the heart to beat irregularly, too quickly, or too slowly, leading to symptoms like chest pain, shortness of breath, and fainting. Factors such as stress, caffeine, alcohol, nicotine, cocaine, certain drugs, congenital defects, diseases, and electrolyte abnormalities can trigger arrhythmias.
Arrhythmias are categorized by their speed, rhythm, and origin. A slow heart...
Dysrhythmias V: Evaluating Dysrhythmias01:30

Dysrhythmias V: Evaluating Dysrhythmias

Dysrhythmias, also known as arrhythmias, are disturbances in the heart's rhythm that range from benign to life-threatening. A thorough evaluation is crucial for appropriate management and involves a comprehensive medical history, physical examination, and various diagnostic tests.Medical HistorySymptoms: Collect detailed information on palpitations, dizziness, syncope, chest pain, and fatigue. Note their onset, frequency, and triggers.Previous Cardiac Issues: Document any history of heart...

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Related Experiment Video

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Methods for ECG Evaluation of Indicators of Cardiac Risk, and Susceptibility to Aconitine-induced Arrhythmias in Rats Following Status Epilepticus
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Methods for ECG Evaluation of Indicators of Cardiac Risk, and Susceptibility to Aconitine-induced Arrhythmias in Rats Following Status Epilepticus

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Electrocardiographic changes in chronic schizophrenic patients.

S H Nizamie1, S Sharma

  • 1Assistant Professor of Psychiatry, Central Institute of Psychiatry, Kanke, Ranchi.

Indian Journal of Psychiatry
|September 20, 2011
PubMed
Summary

This study investigated electrocardiogram (ECG) changes in schizophrenic patients treated with Trifluoperazine. Results showed notable ECG alterations, particularly in the experimental group and older patients.

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Methods for ECG Evaluation of Indicators of Cardiac Risk, and Susceptibility to Aconitine-induced Arrhythmias in Rats Following Status Epilepticus
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Area of Science:

  • Cardiology
  • Psychiatry
  • Pharmacology

Background:

  • Schizophrenia treatment often involves antipsychotic medications.
  • Trifluoperazine is a commonly used antipsychotic.
  • Electrocardiogram (ECG) monitoring is important for cardiac safety during treatment.

Purpose of the Study:

  • To compare electrocardiogram (ECG) variables in schizophrenic patients receiving Trifluoperazine.
  • To assess the impact of Trifluoperazine on cardiac electrical activity.
  • To identify patient subgroups potentially at higher risk for ECG changes.

Main Methods:

  • Two groups of schizophrenic patients (N=43 experimental, N=60 control) were studied.
  • The experimental group received 4 mg of Trifluoperazine daily via intramuscular injection for five days.
  • A 12-lead ECG was recorded three times for each patient.

Main Results:

  • Statistical analysis revealed significant changes in multiple ECG variables.
  • The experimental group, receiving Trifluoperazine, exhibited more pronounced ECG alterations compared to the control group.
  • Patients over 45 years of age showed a greater number of ECG changes.

Conclusions:

  • Trifluoperazine administration is associated with detectable changes in ECG parameters in schizophrenic patients.
  • Age appears to be a factor influencing the extent of ECG alterations.
  • Further cardiac monitoring may be warranted for schizophrenic patients on Trifluoperazine, especially older individuals.