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Updated: May 29, 2026

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Published on: November 21, 2013
Myxoedema presenting with psychosis
Indian Journal of Psychiatry
|September 20, 2011
Summary
This case report highlights hypothyroidism as a cause of psychotic manifestations. Prompt diagnosis and thyroxine supplementation led to significant patient improvement.
Area of Science:
- Endocrinology
- Psychiatry
- Internal Medicine
Background:
- Psychotic manifestations can be challenging to diagnose.
- Underlying medical conditions can present with psychiatric symptoms.
Purpose of the Study:
- To report a case of hypothyroidism presenting with psychotic manifestations.
- To emphasize the importance of considering medical causes for psychosis.
Main Methods:
- Case report of a female patient.
- Clinical history and physical examination.
- Laboratory confirmation of hypothyroidism.
- Treatment with thyroxine supplementation.
Main Results:
- Patient presented with frank psychotic manifestations.
- Hypothyroidism was identified as the underlying cause.
- Thyroxine supplementation resulted in symptom resolution.
Conclusions:
- Hypothyroidism should be considered in the differential diagnosis of psychosis.
- Endocrine disorders can mimic primary psychiatric conditions.
- Timely diagnosis and treatment are crucial for patient recovery.
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