Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Imaging Studies IV: Magnetic Resonance Imaging01:27

Imaging Studies IV: Magnetic Resonance Imaging

Introduction:Magnetic Resonance Imaging, or MRI, can include a specialized imaging technique of the urinary system known as Magnetic Resonance Urography (MRU). This radiation-free technique uses strong magnetic fields and radio waves to produce detailed images with the help of a computer. MRU is particularly effective for visualizing fluid-filled structures like the kidneys, ureters, and bladder.Applications of MRI in the Genitourinary SystemKidneys and Ureters: MRI detects tumors, cysts,...
Magnetic Resonance Imaging01:24

Magnetic Resonance Imaging

Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...
Imaging Studies I: CT and MRI01:14

Imaging Studies I: CT and MRI

Introduction: MRI and CT scans are crucial advancements in medical imaging techniques, playing a vital role in diagnosing conditions related to the gastrointestinal (GI) system. Each scan serves distinct purposes, targets specific areas, and requires unique nursing duties.
Description of the Procedures
Computed Tomography (CT) scan:
Computed Tomography (CT) scans use X-ray technology to generate detailed images of bones, organs, and tissues. During the scan, the patient lies on a moving table...
Anatomical Positions01:11

Anatomical Positions

In anatomy, several standard anatomical positions are used as references for describing the position and orientation of different body parts. These positions help provide a common frame of reference when discussing anatomical structures. The anatomical position is the standard reference point for describing the body's position and orientation. In this position:
The body is upright, facing forward, and standing erect.
The feet are parallel and flat on the floor.
The arms are hanging by the...
Imaging Studies for Cardiovascular System IV: CMRI01:21

Imaging Studies for Cardiovascular System IV: CMRI

Cardiovascular magnetic resonance imaging, or CMRI, is a non-invasive diagnostic test that employs a magnetic field and radiofrequency waves to create precise images of the heart and arteries. It provides comprehensive information about cardiac anatomy, function, perfusion, and tissue characterization without ionizing radiation.IndicationsCMRI diagnoses various heart conditions, including tissue damage from heart attacks, ischemic heart disease, myocarditis, aortic issues (tears, aneurysms,...
Radiological Investigation II: MRI and Ventilation Perfusion Scan01:30

Radiological Investigation II: MRI and Ventilation Perfusion Scan

Description
Magnetic Resonance Imaging (MRI) and Ventilation Perfusion Scans are two radiological investigations that offer detailed diagnostic images of the body, particularly lung structures.
MRI
MRI uses magnetic fields and radiofrequency signals to distinguish between normal and abnormal tissues. This technology provides a more detailed diagnostic image than CT scans, enabling it to characterize pulmonary nodules, stage bronchogenic carcinoma, and evaluate inflammatory activity in...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

High-Risk Benign Breast Lesions: An Ontario Health (Cancer Care Ontario) Recommendations Report.

Current oncology (Toronto, Ont.)·2026
Same author

Associations between clinical pathway concordance, cost, and survival outcomes for stage II colon cancer: a population-based study.

International journal for quality in health care : journal of the International Society for Quality in Health Care·2023
Same author

The effect of age on the opportunity to receive cancer treatment.

Cancer epidemiology·2022
Same author

Identifying Breast Cancer Recurrence in Administrative Data: Algorithm Development and Validation.

Current oncology (Toronto, Ont.)·2022
Same author

Patient opinions on contralateral prophylactic mastectomy: A patient-driven discussion in need of tuning?

Canadian journal of surgery. Journal canadien de chirurgie·2022
Same author

Development of population-level colon cancer pathway concordance measures and association with survival.

International journal of cancer·2022

Related Experiment Video

Updated: May 29, 2026

Tracking the Mammary Architectural Features and Detecting Breast Cancer with Magnetic Resonance Diffusion Tensor Imaging
15:48

Tracking the Mammary Architectural Features and Detecting Breast Cancer with Magnetic Resonance Diffusion Tensor Imaging

Published on: December 15, 2014

Supine breast MRI.

Peter Siegler1, Claire M B Holloway, Petrina Causer

  • 1Sunnybrook Health Sciences Centre, Division of Imaging Research, Toronto, ON, Canada. peter.siegler@hologic.com

Journal of Magnetic Resonance Imaging : JMRI
|September 20, 2011
PubMed
Summary
This summary is machine-generated.

This study introduces a specialized setup for breast magnetic resonance imaging (MRI) performed while the patient lies on their back. By using a flexible coil and motion-correction software, the researchers achieved high-quality images that match standard diagnostic scans. This approach helps bridge the gap between imaging and surgical procedures, which are typically done in this position.

Keywords:
magnetic resonance imagingrespiratory motion compensationbreast-conserving surgeryimage-guided biopsy

Frequently Asked Questions

More Related Videos

Noninvasive In Vivo Small Animal MRI and MRS: Basic Experimental Procedures
12:27

Noninvasive In Vivo Small Animal MRI and MRS: Basic Experimental Procedures

Published on: October 20, 2009

Whole-body PET/MRI of Pediatric Patients: The Details That Matter
10:02

Whole-body PET/MRI of Pediatric Patients: The Details That Matter

Published on: December 19, 2017

Related Experiment Videos

Last Updated: May 29, 2026

Tracking the Mammary Architectural Features and Detecting Breast Cancer with Magnetic Resonance Diffusion Tensor Imaging
15:48

Tracking the Mammary Architectural Features and Detecting Breast Cancer with Magnetic Resonance Diffusion Tensor Imaging

Published on: December 15, 2014

Noninvasive In Vivo Small Animal MRI and MRS: Basic Experimental Procedures
12:27

Noninvasive In Vivo Small Animal MRI and MRS: Basic Experimental Procedures

Published on: October 20, 2009

Whole-body PET/MRI of Pediatric Patients: The Details That Matter
10:02

Whole-body PET/MRI of Pediatric Patients: The Details That Matter

Published on: December 19, 2017

Area of Science:

  • Diagnostic imaging research within supine breast MRI applications
  • Biomedical engineering and clinical radiology

Background:

Standard diagnostic breast imaging typically requires patients to lie face down. This prone orientation creates a significant mismatch with surgical or biopsy procedures. Most clinical interventions occur while the patient is positioned on their back. No prior work had resolved the difficulty of obtaining high-quality scans in this supine posture. That uncertainty drove the need for specialized hardware and software adaptations. Prior research has shown that breast tissue morphology changes drastically between different body positions. This gap motivated the development of a system that conforms to the patient. The current study addresses these limitations by designing a flexible interface for supine imaging.

Purpose Of The Study:

The aim of this study is to achieve high-quality unilateral supine breast magnetic resonance imaging. This work seeks to facilitate the integration of imaging into various clinical applications. Many surgical procedures and biopsies are performed while the patient is in the supine position. Standard prone imaging often hinders the effective use of these scans for surgical guidance. This gap motivated the researchers to develop a system that bridges the positional mismatch. The authors intended to create a fixture and coil that conform to the patient. They also aimed to incorporate respiratory motion compensation into the imaging sequence. This effort addresses the need for consistent anatomical data across different clinical settings.

Main Methods:

The review approach involved designing a specialized fixture to stabilize the patient. Researchers utilized a flexible four-element receive coil to ensure optimal signal acquisition. They implemented a modified 3D spoiled gradient sequence to handle physiological movement. The team conducted volunteer experiments to refine the hardware configuration. A pilot patient study followed to evaluate the practical performance of the setup. Data collection focused on achieving high-quality images in the supine orientation. The investigators compared these results against standard prone diagnostic protocols. This systematic evaluation confirmed the feasibility of the proposed imaging workflow.

Main Results:

The study reports that the developed system produces images with diagnostic value comparable to standard prone scans. Researchers observed distinct differences in breast shape between the two patient positions. Tissue morphology also showed significant variations when comparing supine and prone orientations. The modified sequence successfully mitigated artifacts caused by breathing. Volunteer testing confirmed the stability of the flexible coil interface. The pilot patient study validated the clinical applicability of the hardware. These findings indicate that supine scans provide accurate anatomical representation. The authors emphasize that the registration of these images supports existing clinical workflows.

Conclusions:

The researchers propose that their novel hardware setup successfully enables high-quality supine breast imaging. This study demonstrates that flexible coil designs allow for close conformity to the breast surface. The authors suggest that respiratory motion compensation is vital for maintaining diagnostic clarity during these scans. They report that the resulting image quality is comparable to standard prone diagnostic procedures. The team highlights that tissue morphology varies significantly between different patient positions. These findings imply that supine imaging could improve the accuracy of image-guided clinical interventions. The authors conclude that this registration process supports procedures like ultrasound-guided biopsies. This work provides a foundation for integrating advanced imaging into routine surgical workflows.

The researchers propose a combination of a custom flexible four-element receive coil and a modified 3D spoiled gradient sequence. This hardware-software pairing allows for patient-specific shaping and active respiratory motion compensation to ensure high diagnostic value.

A specialized fixture and a flexible four-element receive coil were developed. These components allow the imaging hardware to conform closely to the breast tissue, which is necessary for capturing detailed anatomical information while the patient lies on their back.

Respiratory motion compensation is necessary because the chest wall moves during breathing. Without this modification to the 3D spoiled gradient sequence, the images would suffer from artifacts that degrade diagnostic quality, making it impossible to match the clarity of standard prone scans.

The flexible coil serves as the interface for patient-specific shaping. Its role is to maintain close proximity to the breast, ensuring that the signal-to-noise ratio remains high despite the lack of the compression typically provided by prone positioning devices.

The researchers measured variations in breast shape and internal tissue morphology. They compared these findings between supine scans and standard prone diagnostic MRI to demonstrate that the new method captures clinically relevant anatomical data.

The authors propose that registering these supine images will aid clinical applications like breast-conserving surgery. By aligning the MRI data with the patient's actual position during surgery, clinicians may achieve better guidance than with prone-only imaging.