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Updated: May 29, 2026
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Synthesis of Core-shell Lanthanide-doped Upconversion Nanocrystals for Cellular Applications
Published on: November 10, 2017
Applications of upconversion nanoparticles in imaging, detection and therapy
Lei Yin Ang1, Meng Earn Lim, Li Ching Ong
1Division of Bioengineering, Faculty of Engineering, National University of Singapore, 9 Engineering Drive 1, Block EA #03-12, Singapore 117576.
Nanomedicine (London, England)
|September 21, 2011
Summary
Upconversion nanoparticles (UCNs) offer superior photostability and deep tissue penetration for biological applications. Recent advances focus on their use in advanced imaging, detection, and therapeutic strategies.
Area of Science:
- Nanoscience
- Biomedical Engineering
- Materials Science
Background:
- Upconversion nanoparticles (UCNs) are luminescent nanomaterials with advantages over traditional fluorophores.
- UCNs offer high signal-to-noise ratio, excellent photostability, and near-infrared excitation.
- Near-infrared excitation allows for deep tissue penetration and reduced photodamage in biological samples.
Purpose of the Study:
- To review recent developments in the application of UCNs in biological fields.
- To highlight strategies for integrating UCNs into imaging, detection, and therapeutic tools.
- To showcase the potential of UCNs as advanced biomedical tools.
Main Methods:
- Review of recent scientific literature on UCNs in biological applications.
- Analysis of synthesis and modification technologies for UCNs.
- Examination of UCN-based strategies for imaging, detection, and therapy.
Main Results:
- UCNs have demonstrated significant potential in various biological applications.
- Advances in nanoparticle technology have facilitated UCN integration.
- Specific strategies have been developed for UCNs in imaging, detection, and therapy.
Conclusions:
- UCNs are promising nanomaterials for advanced biomedical applications.
- Continued research in UCN synthesis and modification will drive further innovation.
- UCNs are poised to become valuable tools in biological imaging, detection, and therapeutics.
