Related Experiment Video
Updated: May 29, 2026

Corneal Sensitivity Testing Procedure for Ophthalmologic and Optometric Patients
Published on: August 2, 2024
Measurement of corneal sensitivity in 20 ophthalmologically normal alpacas
Anja Welihozkiy1, Daniela Bedenice, Lori Lyn Price
1Department of Clinical Sciences, Tufts Cummings School of Veterinary Medicine, 200 Westboro Rd., North Grafton, MA 01536, USA. anja.welihozkiy@tufts.edu
Objective:
To determine corneal sensitivity in 20 healthy adult alpacas (40 eyes) in order to establish reference values.
Design:
Prospective study.
Animals:
Twenty healthy, adult alpacas.
Procedures:
Corneal sensitivity was determined by the corneal touch threshold (CTT) using a Cochet-Bonnet esthesiometer. Five different regions of the cornea were evaluated (nasal, ventral, lateral, dorsal, and central).
Results:
Corneal touch threshold values (in mm filament length) obtained from five corneal regions demonstrated varying corneal sensitivities. The central region (34.5 ± 7.1 mm) was the most sensitive, followed by the ventral (29.5 ± 7.2 mm), medial (29.3 ± 7.3 mm), dorsal (25.6 ± 6.3 mm), and lateral (21.8 ± 5.7 mm) regions. All pairwise comparisons of regional differences were statistically significant (P < 0.05), except for the comparison between the ventral and medial regions (P = 0.88). Evaluation of the CCT while controlling for age (2-5 years vs. 6-10 years) demonstrated an increased CTT with an increasing age for the central, ventral, medial and lateral regions. A decrease in the CTT of the dorsal region was noted with increasing age.
Conclusion And Clinical Relevance:
Corneal touch threshold values in 40 eyes of 20 healthy adult alpacas were determined using a Cochet-Bonnet esthesiometer. This study demonstrated the central corneal region to be most sensitive. Values obtained may serve as reference values in subsequent studies.
