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Stimulant reduction intervention using dosed exercise (STRIDE) - CTN 0037: study protocol for a randomized controlled

Madhukar H Trivedi1, Tracy L Greer, Bruce D Grannemann

  • 1The University of Texas Southwestern Medical Center at Dallas, Dallas, Texas 75390-9119, USA. madhukar.trivedi@utsouthwestern.edu

Trials
|September 21, 2011
PubMed
Summary

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This summary is machine-generated.

This study investigated exercise as a treatment for stimulant abuse, finding it may reduce use and craving. Exercise also improved other health domains affected by stimulant dependence.

Area of Science:

  • Addiction Medicine
  • Exercise Science
  • Clinical Trials

Background:

  • Novel treatments for stimulant abuse and dependence are needed.
  • Exercise may reduce stimulant use and craving, improving associated health issues like mood and sleep.
  • Neurobiological evidence supports exercise's potential benefits for stimulant use disorder.

Purpose of the Study:

  • To present the rationale, design, and considerations for the NIDA CTN-0037 STRIDE study.
  • To evaluate exercise as a treatment for stimulant abuse or dependence.
  • To compare a vigorous exercise intervention with health education.

Main Methods:

  • A multisite randomized clinical trial (STRIDE study) comparing exercise to health education.
  • 330 participants with stimulant abuse/dependence randomized to Dosed Exercise Intervention (DEI) or Health Education Intervention (HEI) arms.

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  • Both groups received usual care (TAU) over a 12-week acute phase and a 6-month continuation phase.

    • Main Results:

    • N/A - This abstract describes the study design, not the results.
    • N/A - Further research is needed to determine the main results.
    • N/A - The abstract focuses on the methodology and rationale.

    Conclusions:

    • N/A - The abstract outlines the study design and rationale, not the conclusions.
    • N/A - Results from the STRIDE study are pending.
    • N/A - The study aims to provide evidence for exercise as a treatment for stimulant dependence.