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Effectiveness of Biobrane for treatment of partial-thickness burns in children
Aaron P Lesher1, Ryan H Curry, Jill Evans
1Division of Pediatric Surgery, Department of Surgery, Medical University of South Carolina, Charleston, SC 29425-6130, USA.
Insights
Biobrane dressings promote faster healing for partial-thickness burns compared to Beta Glucan Collagen (BGC). This innovative wound care may also reduce hospital stays for pediatric patients requiring admission.
Area of Science:
- Pediatric Burn Care
- Wound Healing Dressings
- Regenerative Medicine
Background:
- Effective partial-thickness burn wound care aims to reduce pain, shorten hospital stays, and be versatile.
- Traditional treatments require careful application and management.
Purpose of the Study:
- To compare the effectiveness of Biobrane versus Beta Glucan Collagen (BGC) for treating partial-thickness burns in children.
- To evaluate healing times and hospital length of stay for pediatric burn patients.
Main Methods:
- Retrospective cohort study comparing children treated with Biobrane to historical controls treated with BGC.
- Data collected from a tertiary care pediatric hospital between 2003 and 2009.
- Multivariate statistical analysis used to compare outcomes.
Main Results:
- Biobrane treatment resulted in significantly faster healing times (median 9 days) compared to BGC (median 13 days).
- Patients treated with Biobrane showed a trend toward shorter hospital stays (2.6 days) versus BGC (4.1 days).
- Study included 235 pediatric patients with an average of 6.0% body surface area partial-thickness burns.
Conclusions:
- Biobrane dressings are effective for partial-thickness burn wound care, leading to accelerated healing.
- Biobrane may reduce the length of hospital stay for pediatric patients requiring inpatient care.
- Early debridement and appropriate dressing application are crucial for optimal burn wound management.
Purpose:
Wound care for partial-thickness burns should alleviate pain, decrease hospital length of stay, and be readily applied to a variety of wounds. The effectiveness of Biobrane (UDL Laboratories, Rockford, IL) is compared with that of Beta Glucan Collagen (BGC; Brennan Medical, St. Paul, MN) in a retrospective cohort study.
Methods:
A retrospective chart review of all children treated at a tertiary care pediatric hospital between 2003 and 2009 identified patients with partial-thickness burns treated with Biobrane. These patients were compared with historical controls treated with BGC.
Results:
A total of 235 children between the ages of 4 weeks and 18 years with an average of 6.0% body surface area partial-thickness burns were treated with Biobrane. In a multivariate statistical analysis, patients treated with Biobrane healed significantly faster than those treated with BGC (Biobrane vs BGC: median, 9 vs 13 days; P = .019; hazard ratio, 1.68). In addition, patients who required inpatient treatment trended toward having shorter length of hospital stay in the Biobrane group (2.6 vs 4.1 days, P = .079).
Conclusion:
Partial-thickness burn care consists of early debridement and application of a burn wound dressing. Biobrane dressings result in faster healing compared with BGC and may decrease hospital length of stay for patients requiring inpatient admission.
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