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Colorectal anomalies in patients with classic bladder exstrophy

Andrew A Stec1, Nima Baradaran, Christine Tran

  • 1Division of Pediatric Urology, The Brady Urological Institute, The Johns Hopkins Medical Institutions, Baltimore, MD 21287, USA. andrew.stec@jhmi.edu

Journal of Pediatric Surgery
|September 21, 2011
PubMed

Insights

Children with classic bladder exstrophy (CBE) have a 1.8% rate of colorectal anomalies, primarily imperforate anus. Early evaluation and treatment are crucial for managing these significant associated conditions.

Area of Science:

  • Pediatric Surgery
  • Congenital Anomalies
  • Urology

Background:

  • Classic bladder exstrophy (CBE) is a complex congenital condition affecting the genitourinary system.
  • Associated gastrointestinal malformations in CBE patients are not well-characterized.
  • Understanding these comorbidities is vital for comprehensive patient care.

Purpose of the Study:

  • To determine the incidence and types of colorectal anomalies in children with CBE.
  • To assess the significance of these anomalies in the context of CBE.

Main Methods:

  • Retrospective review of a database of 1044 patients with bladder exstrophy-epispadias-cloacal exstrophy complex.
  • Detailed medical record review for 676 patients diagnosed with CBE.
  • Identification and extraction of history for patients with gastrointestinal malformations.

Main Results:

  • 12 out of 676 patients with CBE (1.8%) had a concomitant colorectal anomaly.
  • Imperforate anus was the most common anomaly (8 patients).
  • Other anomalies included severe rectal stenosis (2 patients) and congenital rectal prolapse (2 patients).

Conclusions:

  • Isolated colorectal anomalies occur in 1.8% of children with CBE, a 72-fold increase over the general population.
  • Despite being uncommon, these anomalies carry significant morbidity.
  • Prompt evaluation and treatment of both genitourinary and colorectal issues are essential.
Abstract

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