COSEHC global vascular risk management quality improvement program: rationale and design

Area of Science:

• Cardiology
• Public Health
• Epidemiology

Background:

• The Consortium for Southeastern Hypertension Control (COSEHC) focuses on managing global risk factors in metabolic syndrome patients.
• The COSEHC Global Vascular Risk Management Study (GVRM) aims to assess the impact of these management strategies on patient outcomes.
• This study evaluates baseline demographics and risk scores within the GVRM cohort.

Purpose of the Study:

• To present baseline demographics of patients in the GVRM study.
• To calculate a modified COSEHC risk score using 11 variables (COSEHC-11).
• To compare the COSEHC-11 score with existing risk scores: COSEHC-17, Framingham, PROCAM, and SCORE.

Main Methods:

• Utilized deidentified electronic medical records for risk score calculation.
• Assessed the predictive ability of COSEHC-11 for the COSEHC-17 score using regression analysis.
• Converted raw scores to estimated probabilities of fatal coronary heart disease (CHD) and compared with other algorithms.

Main Results:

• Analyzed data from 43,676 patients with complete data for 11 variables out of 177,404 enrolled.
• The COSEHC-11 score averaged 31.75 ± 11.66, indicating a 1.4% five-year fatal CHD risk.
• COSEHC-11 demonstrated high predictability for COSEHC-17 (R(2) = 0.93; P < 0.0001) and correlated well with SCORE.

Conclusions:

• The COSEHC-11 risk score is statistically comparable to the COSEHC-17 score.
• COSEHC-11 is a viable tool for assessing five-year cardiovascular mortality risk.
• This simplified score can aid in global vascular risk management for patients with metabolic syndrome.